Simkania negevensis, an example of the diversity of the antimicrobial susceptibility pattern among Chlamydiales [PublishAheadOfPrint]

Over the last years, several Chlamydia-related bacteria have been discovered, including Simkania negevensis, the founding member of the Simkaniaceae family. We evaluated the antimicrobial susceptibility patterns of this emerging intracellular bacterium and highlighted significant differences with other related Chlamydiales. S. negevensis was susceptible to macrolides, clindamycin, cyclines, rifampicin and quinolones. Importantly, unlike other Chlamydiales, treatment with β-lactams and vancomycin did not induce the formation of aberrant bodies leading to a complete resistant phenotype.

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