Hypertrophic Cardiomyopathy in Childhood: Risk Management Through Family Screening

The spectrum of hypertrophic cardiomyopathy (HCM) ranges from silent phenotypes, typically with mild hypertrophy in asymptomatic patients, to aggressive phenotypes with malignant arrhythmias or hemodynamic compromise in patients with severe hypertrophy and disabling symptoms. This is true for adult patients as well as for children with HCM. Reports depicting worst-case scenarios of severe progressive hypertrophy and clinical deterioration in childhood tend to dominate the literature on childhood HCM, and few population studies have been published.

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