Colonized Egyptian fruit bats (Rousettus aegyptiacus), originating in South Africa, were inoculated subcutaneously with Ebola virus (EBOV). No overt signs of morbidity, mortality, or gross lesions were noted. Bats seroconverted by Day 10–16 post inoculation (p.i.), with the highest mean anti-EBOV IgG level on Day 28 p.i. EBOV RNA was detected in blood from one bat. In 16 other tissues tested, viral RNA distribution was limited and at very low levels. No seroconversion could be demonstrated in any of the control bats up to 28 days after in-contact exposure to subcutaneously-inoculated bats. The control bats were subsequently inoculated intraperitoneally, and intramuscularly with the same dose of EBOV. No mortality, morbidity or gross pathology was observed in these bats. Kinetics of immune response was similar to that in subcutaneously-inoculated bats. Viral RNA was more widely disseminated to multiple tissues and detectable in a higher proportion of individuals, but consistently at very low levels. Irrespective of the route of inoculation, no virus was isolated from tissues which tested positive for EBOV RNA. Viral RNA was not detected in oral, nasal, ocular, vaginal, penile and rectal swabs from any of the experimental groups.
from #Medicine via ola Kala on Inoreader http://ift.tt/1WAE2jb
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
-
▼
Ιανουαρίου
(578)
-
▼
Ιαν 22
(47)
- Downstream assessment of chlorinated organic compo...
- Respiratory hypoalgesia? Breath-holding, but not r...
- Eugenol, α-pinene and β-caryophyllene from Plectra...
- Inactivation of Cryptosporidium parvum under labor...
- Amebicidal activity of the essential oils of Lippi...
- Increased Gal-9 and Tim-3 expressions during liver...
- Improvement on the extraction method of RNA in mit...
- The potential application of plant essential oils ...
- Origins of Wohlfahrtia magnifica in Italy based on...
- Hepatozoon ellisgreineri n. sp. (Hepatozoidae): de...
- New insights into diagnosis of Platynosomum fastos...
- Dynamics of Th17 associating cytokines in Cryptosp...
- Screening and characterization of early diagnostic...
- A new coccidian, Isospora parnaitatiaiensis n. sp....
- Isolation of Balamuthia mandrillaris from soil sam...
- Seroprevalence, isolation, first genetic character...
- Survey for Toxoplasma gondii by PCR detection in m...
- No evidence of Dirofilaria repens infection in red...
- Larvicidal efficacy and chemical constituents of O...
- Zoonotic ocular onchocercosis caused by Onchocerca...
- Intraspecific and interspecific genetic variation ...
- Influence of season and site location on European ...
- Metal-based biologically active azoles and β-lacta...
- A potent and selective inhibitor targeting human a...
- Structure–activity relationship study of 4-(thiazo...
- Sulfonamide inhibition studies of the β-carbonic a...
- In vitro interactions between Anidulafungin and no...
- From Indole to Pyrrole, Furan, Thiophene and Pyrid...
- Heptapeptide Ligands against Receptor-Binding Site...
- Synthesis of 3-acyloxyxanthone derivatives as α-gl...
- Geosciences, Vol. 6, Pages 6: Acknowledgement to R...
- JDB, Vol. 4, Pages 4: Cell Fate Decisions During B...
- Viruses, Vol. 8, Pages 29: Experimental Inoculatio...
- Healthcare, Vol. 4, Pages 12: Acknowledgement to R...
- IJFS, Vol. 4, Pages 2: Acknowledgement to Reviewer...
- Insects, Vol. 7, Pages 4: Oviposition by Female Pl...
- JFB, Vol. 7, Pages 3: Acknowledgement to Reviewers...
- Land, Vol. 5, Pages 1: Assessing and Governing Eco...
- Editorial Board
- Table of Contents
- Sex, Gender, and Traumatic Brain Injury: A Commentary
- Chemosensors, Vol. 4, Pages 2: Acknowledgement to ...
- Electronics, Vol. 5, Pages 6: Acknowledgement to R...
- Approach-motivated pregoal states enhance the rewa...
- Medical Sciences, Vol. 4, Pages 2: Acknowledgement...
- IJERPH, Vol. 13, Pages 150: Acknowledgement to Rev...
- Agronomy, Vol. 6, Pages 6: Acknowledgement to Revi...
-
▼
Ιαν 22
(47)
Αναζήτηση αυτού του ιστολογίου
Παρασκευή 22 Ιανουαρίου 2016
Viruses, Vol. 8, Pages 29: Experimental Inoculation of Egyptian Fruit Bats (Rousettus aegyptiacus) with Ebola Virus
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.