The aim was to investigate the prevalence of non-alcoholic steatohepatitis (NASH) and risk factors for hepatic fibrosis in morbidly obese patients submitted to bariatric surgery. This retrospective study recruited all patients submitted to bariatric surgery from January 2007 to December 2012 at a reference attendance center of Southern Brazil. Clinical and biochemical data were studied as a function of the histological findings of liver biopsies done during the surgery. Steatosis was present in 226 (90.4%) and NASH in 176 (70.4%) cases. The diagnosis of cirrhosis was established in four cases (1.6%) and fibrosis in 108 (43.2%). Risk factors associated with NASH at multivariate analysis were alanine aminotransferase (ALT) >1.5 times the upper limit of normal (ULN); glucose ≥ 126 mg/dL and triglycerides ≥ 150 mg/dL. All patients with ALT ≥1.5 times the ULN had NASH. When the presence of fibrosis was analyzed, ALT > 1.5 times the ULN and triglycerides ≥ 150 mg/dL were risk factors, furthermore, there was an increase of 1% in the prevalence of fibrosis for each year of age increase. Not only steatosis, but NASH is a frequent finding in MO patients. In the present study, ALT ≥ 1.5 times the ULN identifies all patients with NASH, this finding needs to be further validated in other studies. Moreover, the presence of fibrosis was associated with ALT, triglycerides and age, identifying a subset of patients with more severe disease.
from #Medicine via ola Kala on Inoreader http://ift.tt/1jDRBAH
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
-
▼
2015
(2119)
- ► Δεκεμβρίου (940)
-
▼
Οκτωβρίου
(414)
-
▼
Οκτ 23
(49)
- NBI to Detect Post-RT Mucosal Residual NPC
- Different target specificities of haptoglobin and ...
- Zeaxanthin and α-tocopherol reduce the inhibitory ...
- Saikosaponin a inhibits lipopolysaccharide-oxidati...
- Role of NOS2 in Pulmonary Injury and Repair in Res...
- Glutathione, glutathione disulfide, and S-glutathi...
- Left ventricular diastolic dysfunction in Nrf2 kno...
- Membranes, Vol. 5, Pages 646-663: Membrane and Pro...
- Microarrays, Vol. 4, Pages 490-502: SNP Analysis a...
- Membranes, Vol. 5, Pages 632-645: High Temperature...
- Atmosphere, Vol. 6, Pages 1578-1589: Radiation Bal...
- Metals, Vol. 5, Pages 1957-1970: Resistance of Hyd...
- Microorganisms, Vol. 3, Pages 725-745: Dynamic In ...
- Metals, Vol. 5, Pages 1921-1956: Hydrometallurgica...
- PT -symmetric dimer of coupled nonlinear oscillators
- Toxins, Vol. 7, Pages 4330-4349: AFM1 in Milk: Phy...
- Toxins, Vol. 7, Pages 4315-4329: Menadione-Induced...
- Toxins, Vol. 7, Pages 4294-4314: Detoxification of...
- Symmetry, Vol. 7, Pages 1945-1980: New Security De...
- Molbank, Vol. 2015, Article M869: 7-Iodo-1H-indole...
- Symmetry, Vol. 7, Pages 1929-1944: An Application ...
- Nutrients, Vol. 7, Pages 8830-8845: No Effect of A...
- Pathogens, Vol. 4, Pages 722-738: Differential Con...
- Sustainability, Vol. 7, Pages 14371-14384: Typolog...
- Religions, Vol. 6, Pages 1263-1276: The Role of Re...
- Sustainability, Vol. 7, Pages 14358-14370: Team Or...
- Sports, Vol. 3, Pages 281-301: Outcomes following ...
- Marine Drugs, Vol. 13, Pages 6537-6549: Production...
- Aerospace, Vol. 2, Pages 602-626: Optimization of ...
- Water, Vol. 7, Pages 5831-5848: Experiments and Nu...
- Agronomy, Vol. 5, Pages 491-505: Performance of No...
- Submaximal exercise based equations to predict max...
- Influence of the number of predicted words on text...
- Depression trajectories during the first year afte...
- A locomotor adaptability task promotes intense and...
- Putting physical activity whilst experiencing low ...
- Perception of muscular effort during dynamic elbow...
- ENT Medicine
- Water, Vol. 7, Pages 5806-5830: Methods of the Wat...
- Water, Vol. 7, Pages 5788-5805: Spatio-Temporal Pa...
- IJMS, Vol. 16, Pages 25552-25559: Non-Alcoholic St...
- IJMS, Vol. 16, Pages 25536-25551: Cell Death Conve...
- IJMS, Vol. 16, Pages 25516-25535: Molecular Clonin...
- Polymers, Vol. 7, Pages 2131-2145: Maleimide-Funct...
- IJMS, Vol. 16, Pages 25502-25515: The Fab Fragment...
- IJMS, Vol. 16, Pages 25476-25501: Stem Cells in Sk...
- Polymers, Vol. 7, Pages 2119-2130: PEGylated Fluor...
- IJMS, Vol. 16, Pages 25466-25475: Photodynamic The...
- Marine Drugs, Vol. 13, Pages 6521-6536: Simultaneo...
-
▼
Οκτ 23
(49)
Αναζήτηση αυτού του ιστολογίου
Παρασκευή 23 Οκτωβρίου 2015
IJMS, Vol. 16, Pages 25552-25559: Non-Alcoholic Steatohepatitis (NASH): Risk Factors in Morbidly Obese Patients
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.