Brain Sciences, Vol. 10, Pages 160: Purinergic Signaling and Related Biomarkers in DepressionBrain Sciences, Vol. 10, Pages 160: Purinergic Signaling and Related Biomarkers in Depression Brain Sciences doi: 10.3390/brainsci10030160 Authors: Francesco Bartoli Geoffrey Burnstock Cristina Crocamo Giuseppe Carrà It is established that purinergic signaling can shape a wide range of physiological functions, including neurotransmission and neuromodulation. The purinergic system may play a role in the pathophysiology...
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Oxidative stress assessment in sickle cell anemia patients treated with hydroxyureaAbstract Hydroxyurea (HU) is used as a therapy in sickle cell anemia (SCA). Many studies have established that HU improves patient quality of life by reducing symptoms. However, the effect of HU on erythrocytes is not well-described. We evaluated several parameters related to oxidative stress and total lipid content of erythrocytes in patients with SCA. The patient cohort consisted of 7 SCA patients treated with HU,...
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pubmed: sleep'Good vibrations': positional treatments for obstructive sleep apnoea.Related Articles'Good vibrations': positional treatments for obstructive sleep apnoea. Thorax. 2020 Mar 08;: Authors: Heinzer R PMID: 32152178 [PubMed - as supplied by publisher]pubmed: sleep20hInfant sleep and child mental health: a longitudinal investigation.Related ArticlesInfant sleep and child mental health: a longitudinal investigation. Arch Dis Child. 2020 Mar 09;: Authors: Cook F, Conway LJ, Giallo R, Gartland...
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pubmed: sleepMemory: Necessary for Deep Sleep?Related ArticlesMemory: Necessary for Deep Sleep? Curr Biol. 2020 Mar 09;30(5):R234-R236 Authors: Saletin JM Abstract Patients with hippocampus lesions suffer profound failures in episodic memory. Sleep plays a key role in processing hippocampus-dependent memories. Lesioning this structure may fundamentally alter the architecture of human sleep, posing fundamental questions about the link between sleep and memory processing.PMID: 32155430 [PubMed - as...pubmed:...
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AA pubmed: head and neckDoes age influence disease-specific survival in patients with squamous cell carcinomas of the head and neck?Related ArticlesDoes age influence disease-specific survival in patients with squamous cell carcinomas of the head and neck? J Surg Oncol. 2020 Mar 09;: Authors: Lop J, Valero C, García J, Quer M, Ganly I, Shah JP, Patel SG, León X Abstract BACKGROUND AND OBJECTIVES: The number of patients diagnosed with head and neck squamous cell carcinoma (HNSCC) at an advanced age...
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Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and agingAbstract Cytomegalovirus (CMV) is one of the largest and most ubiquitous latent persistent viruses. Most humans are infected with CMV early in life, and all immunocompetent humans spend several decades living with CMV. In the vast majority of the hosts, CMV does not cause manifest disease, and CMV therefore can be considered part of normal aging for 50–90% of the human population worldwide. Experimental,...
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Genes, Vol. 11, Pages 298: Population Genetic Structure is Unrelated to Shell Shape, Thickness and Organic Content in European Populations of the Soft-Shell Clam Mya ArenariaGenes, Vol. 11, Pages 298: Population Genetic Structure is Unrelated to Shell Shape, Thickness and Organic Content in European Populations of the Soft-Shell Clam Mya Arenaria Genes doi: 10.3390/genes11030298 Authors: De Noia Telesca Vendrami Gokalp Charrier Harper Hoffman The soft-shell clam Mya arenaria is one of the most ancient...
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Viruses, Vol. 12, Pages 305: Barriers to Hepatitis B Screening and Prevention for African Immigrant Populations in the United States: A Qualitative StudyViruses, Vol. 12, Pages 305: Barriers to Hepatitis B Screening and Prevention for African Immigrant Populations in the United States: A Qualitative Study Viruses doi: 10.3390/v12030305 Authors: Catherine Freeland Sierra Bodor Udara Perera Chari Cohen Chronic hepatitis B infection (HBV) disproportionately affects African Immigrant (AI) communities...
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Cancers, Vol. 12, Pages 657: Safety and Effectiveness of Aflibercept + Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) for the Treatment of Patients with Metastatic Colorectal Cancer (mCRC) in Current Clinical Practice: OZONE StudyCancers, Vol. 12, Pages 657: Safety and Effectiveness of Aflibercept + Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) for the Treatment of Patients with Metastatic Colorectal Cancer (mCRC) in Current Clinical Practice: OZONE Study Cancers doi: 10.3390/cancers12030657...
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edoc: No conditions. Results ordered -Date Deposited.Immobilized ProteinâEuro" Polymer NanoreactorsSurface-immobilized nanoscale reactors utilizing membrane protein channels are used to generate precisely patterned chemically and biologically active surfaces (see image). The enzymatic conversion of a fluorogenic substrate in the cavity of immobilized nanoreactors is a model reaction demonstrating future potential application of the system in sensors, analytics, microfluidics, and single-molecule...
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ScienceDirect Publication: Cell ReportsDetection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic SignaturesPublication date: 10 March 2020Source: Cell Reports, Volume 30, Issue 10Author(s): Pierre Billon, Tarun S. Nambiar, Samuel B. Hayward, Maria P. Zafra, Emma M. Schatoff, Koichi Oshima, Andrew Dunbar, Marco Breinig, Young C. Park, Han S. Ryu, Darjus F. Tschaharganeh, Ross L. Levine, Richard Baer, Adolfo Ferrando, Lukas E. Dow, Alberto CicciaScienceDirect...
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Clinical, pathological and genetic spectrum in 89 cases of mitochondrial progressive external ophthalmoplegiaBackgroundMitochondrial progressive external ophthalmoplegia (PEO) encompasses a broad spectrum of clinical and genetic disorders. We describe the phenotypic subtypes of PEO and its correlation with molecular defects and propose a diagnostic algorithm.MethodsRetrospective analysis of the clinical, pathological and genetic features of 89 cases.ResultsThree main phenotypes were found: 'pure...
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Mycobacterium hassiacum: a thermophilic Mycobacterium species to demonstrate thermal disinfection of medical devicesReprocessing reusable medical devices is crucial in the healthcare industry. To ensure patient safety, strict standards are dictated to validate thermal disinfection in automated washer-disinfectors. The Unite...BMC Research Notes - Latest Articles11hN,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine, a zinc chelator, inhibits biofilm and hyphal formation in Trichosporon asahiiTrichosporon...
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Intranasal pain in a patient with Behcet's disease: A 52 year old woman with Behçet's disease presented with two to three days of severe pain in her left nostril. She had Behçet's associated bowel, oral, and cerebral vasculitis and had been taking...
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Tiny birdlike dinosaur species identified from skull trapped in amberA new species of dinosaur has been named from a skull measuring only 1.4 centimetres across. The dinosaur was smaller than any living bird todayNew Scientist - The Human Brain13hWhy is it so hard to calculate how many people will die from covid-19?It might seem confusing that estimates of number of fatalities caused by the new coronavirus range widely, but that's because there is no one fixed death rateNew Scientist - The Human...
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A comprehensive analysis of e-waste legislation worldwideAbstract The improper disposal and informal processing of e-waste have raised serious concerns for the environment and human health worldwide. A variety of legislative frameworks have been implemented to regulate e-waste management and upcycling in order to prevent environmental pollution and adopt resource reuse. Current e-waste legislation in different countries mostly include restrictions on e-waste import/export, regulations for recycling...
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After-hours radiology coverage in children's hospitals: a multi-center surveyAbstract Background Although the provision of pediatric emergency and trauma radiology has become increasingly prevalent in North America over the last few years, many hospitals differ in their models of providing after-hours coverage. Objective To describe the scope of after-hours radiology services provided in children's hospitals in North America, and...Latest ResultsnowMark above section as read Cancer Prevention Research...
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Comparison of the effect of Roux‐en‐Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes: A systematic review and meta‐analysis of randomized controlled trials: SummaryBariatric surgery is an effective treatment option for patients with type 2 diabetes mellitus (T2DM) and obesity. This study aims to compare the effects of Roux‐en‐Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on remission of T2DM. MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were...
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Bilateral Femoral Neuropathy: A Rare Complication of Drug Overdose due to Prolonged Posturing in Lithotomy Position: Background. Bilateral femoral neuropathy is an uncommon complication of various surgical and nonsurgical procedures, such as pelvic/abdominal surgery or vaginal delivery. Case Report. We report a case of a 41-year-old male who was found unresponsive against the wall in a "lithotomy-type" position with both knees flexed at approximately 90 degrees and both hips flexed and externally...
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Adjuvant Therapies in Diabetic Retinopathy as an Early Approach to Delay Its Progression: The Importance of Oxidative Stress and Inflammation: Diabetes mellitus (DM) is a progressive disease induced by a sustained state of chronic hyperglycemia that can lead to several complications targeting highly metabolic cells. Diabetic retinopathy (DR) is a multifactorial microvascular complication of DM, with high prevalence, which can ultimately lead to visual impairment. The genesis of DR involves a complex...
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Comparative study between topically applied irradiated human amniotic membrane in combination with tea tree oil versus topical tioconazole in pityraisis versicolor treatment: AbstractPityriasis versicolor (PV) is a chronic skin disease caused by virulence activities of Malassezia, a genus of skin-associated yeasts. Traditionally, Tioconazole is used as a topical antifungal for curing PV. Previous investigations cited that human amniotic membrane (HAM), a placental tissue, has antimicrobial and anti-inflammatory...
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Antimicrobial Effect of a Peptide Containing Novel Oral Spray on Streptococcus mutans: Objective. To investigate the antibacterial effect of a novel antimicrobial peptide containing oral spray GERM CLEAN on Streptococcus mutans (S. mutans) in vitro and further explore the related mechanisms at phenotypic and transcriptional levels. Methods. The disk diffusion method was used to preliminarily appraise the antimicrobial effect of GERM CLEAN. The minimal inhibitory concentration (MIC) of GREM CLEAN...
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Endovascular Treatment of Venous Bypass Graft Pseudoaneurysm with the New Solaris Self-Expanding Covered Stent: Nonanastomotic pseudoaneurysm formation after vascular reconstruction is a rarely encountered problem. Covered stent graft constitutes a minimal approach. To our knowledge, the present study constitutes the first case of implantation of Solaris stent graft in Europe. A 69-year-old man with severe cardiac dysfunction presented a pseudoaneurysm of a popliteal to popliteal artery reversed...
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Diabetes, Fetal Demise, and Shoulder Dystocia: The Importance of Glucose Screening to Prevent Catastrophic Obstetric Outcomes: Diabetes is associated with increased risk of stillbirth and shoulder dystocia. Compared with uncomplicated pregnancies, diabetic patients have a 4-6x risk of stillbirth and 2-3x risk of shoulder dystocia. A 34 yo G2P0010 presented with a 40+3 wga IUFD with nonstandard antenatal glucose screening. Admission labs included a hemoglobin A1c of 6.6. She had a vaginal delivery...
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Optimal Decisions and Pricing in Mail Service Systems Subject to Virus Attacks: We consider an optimal decision problem of the service providers in public mail service systems subject to virus attacks. Two scenarios, i.e., free service systems and payment systems, are investigated in the paper. We first formulate the considered system as a partially observable queue with Bernoulli vacations, and by the supplementary variable method, we obtain some performance measures of the system. In the case...
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A Cardiac Pseudoaneurysm as a Thromboembolic Source: Acute Visual Loss due to Cardiac Emboli: Acute visual loss is rarely caused by a heart condition. This manuscript transcribes a case report of a 36-year-old patient with a 2-year history of aortic valve replacement due to bicuspid aortic valve endocarditis that presents to the emergency department with an acute right eye visual loss. After ophthalmologic investigation identified a central retinal artery occlusion, a transthoracic echocardiography...
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Effect of Intestinal Levodopa-Carbidopa Infusion on Pharyngeal Dysphagia: Results from a Retrospective Pilot Study in Patients with Parkinson's Disease: Background. Pharyngeal dysphagia is a common symptom of Parkinson's disease (PD) leading to severe complications. PD-related pharyngeal dysphagia (PDrPD) may significantly improve in up to half of patients following acute oral levodopa challenge. Objective. The aim of this study was to investigate the effects of levodopa-carbidopa intestinal gel...
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Subcutaneously Anchored Sutureless Device for Securement of Chest Tubes in Neonates with Pleural Effusion: Three Case Reports: We report the clinical cases of three neonates, all of them premature, requiring the placement of a chest tube for drainage of a massive pleural effusion. In all three patients, the chest tube was secured using a new subcutaneously anchored sutureless system. This new securement device was easy to insert and to remove, and highly effective in preventing dislodgment. Also,...
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Detection of Moderate Traumatic Brain Injury from Resting-State Eye-Closed Electroencephalography: Traumatic brain injury (TBI) is one of the injuries that can bring serious consequences if medical attention has been delayed. Commonly, analysis of computed tomography (CT) or magnetic resonance imaging (MRI) is required to determine the severity of a moderate TBI patient. However, due to the rising number of TBI patients these days, employing the CT scan or MRI scan to every potential patient is not...
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Arsenic Trioxide Treatment during Pregnancy for Acute Promyelocytic Leukemia in a 22-Year-Old Woman: Acute leukemia during pregnancy is rare (1 for 100000 pregnancies). The association of arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) is known as the best therapy in standard-risk acute promyelocytic leukemia (APL). We describe the first case of a pregnancy with ATRA and ATO reported in the literature. In March 2018 at the University Hospital of Besançon, a 22-year-old woman was diagnosed...
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Application of Optimal Control to Influenza Pneumonia Coinfection with Antiviral Resistance: Influenza and pneumonia independently lead to high morbidity and mortality annually among the human population globally; however, a glaring fact is that influenza pneumonia coinfection is more vicious and it is a threat to public health. Emergence of antiviral resistance is a major impediment in the control of the coinfection. In this paper, a deterministic mathematical model illustrating the transmission...
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Adult Ectopic Cervical Thymic Tissue in relation to a Parathyroid Adenoma and a Papillary Thyroid Carcinoma: A Report of Two Cases: Ectopic cervical thymus is a rare congenital anomaly, which results because of the failure of complete descent of the thymus. They are incidental findings in the young and may disappear during the early years of life; however, they have rarely been described in adults. Some of them may undergo hyperplasia or neoplastic transformation and become visible or cause symptoms....
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Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection Treated at the Vietnam National Children's Hospital: Lower respiratory tract infections are commonly caused by viruses and cause significant morbidity and mortality among children. Early identification of the pathological agent causing these infections is essential to avoid unnecessary antibiotic use and improve patient management. Multiplex PCR techniques were recently developed to detect multiple viral pathogens using...
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Organoids as a Powerful Model for Respiratory Diseases: Insults to the alveoli usually lead to inefficient gas exchange or even respiratory failure, which is difficult to model in animal studies. Over the past decade, stem cell-derived self-organizing three-dimensional organoids have emerged as a new avenue to recapitulate respiratory diseases in a dish. Alveolar organoids have improved our understanding of the mechanisms underlying tissue homeostasis and pathological alterations in alveoli. From...
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One Lung Soldier: A Ventilation Conundrum in a Postpneumonectomy Syndrome Complicated by Acute Respiratory Syndrome: Postpneumonectomy syndrome involves mediastinal shift causing dynamic airway obstruction via compression of the main bronchus and distal trachea. A few case reports describe the development of ARDS in patients with postpneumonectomy syndrome. Reeb et al. (2017) describe the mortality of postpneumonectomy ARDS anywhere from 33% to 88%. One may encounter difficulty in intubation and...
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Clinical Examination and Self-Reported Upper Extremity Impairments in Patients with Long-Standing Type 1 Diabetes Mellitus: Aim. The aims of the current study were (1) to determine the prevalence of upper extremity impairments (UEIs) in patients with type 1 diabetes by clinical investigation; (2) to investigate if self-reported impairments were concordant with clinical findings and if key questions could be identified; and (3) to investigate if answers to our self-reported questionnaire regarding...
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Time to Recovery from Severe Acute Malnutrition and Its Predictors among Admitted Children Aged 6-59 Months at the Therapeutic Feeding Center of Pawi General Hospital, Northwest Ethiopia: A Retrospective Follow-Up Study: Background. Ethiopia is one of the countries in sub-Saharan Africa with the highest rates of severe acute malnutrition. Early recovery is a performance indicator for severe acute malnourished children for the therapeutic feeding. Despite the available interventions to tackle nutritional...
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Knowledge and sources of information on umbilical cord blood donation in pregnant women: AbstractThe use of umbilical cord blood (UCB) holds promise for the treatment of a wide spectrum of diseases. However, information on UCB donation is not widespread or accurate among expectant women. The aim of this study is to evaluate pregnant women's knowledge of UCB donation, their main sources of information and their satisfaction with the knowledge possessed. Women (N = 375) in the last semester of pregnancy...
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Preliminary studies of hair follicle regeneration by injections of epidermal stem cells and dermal papilla cells into nude mice: AbstractThe ultimate goal of organ regenerative therapy is to reproduce fully functional organs to replace which have been damaged as a result of diseases or injury. Although several studies claimed that using different types of cells in some animal models promote hair follicles regeneration, more researches can be done to develop a sufficient and efficient protocol to...
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The Challenges of Managing Ovarian Cancer in the Developing World: Ovarian cancer has high morbidity and mortality rates among cancers of the reproductive system. The disease typically presents at late stage when the 5-year relative survival rate is only 29%. Similarly, access to prevention, early diagnosis, treatment, and palliative care for cancer-related disease is insufficient. The availability of cancer treatments in Africa is especially poor. Case. A 17-year-old lady, nulliparous, was admitted...
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Increased Vulnerability to Pregnancy and Sexual Violence in Adolescents with Precocious Menstruation
Increased Vulnerability to Pregnancy and Sexual Violence in Adolescents with Precocious Menstruation: This cross-sectional, observational, and descriptive study was conducted to evaluate the association between age at menarche in the adolescent population and the age at sexual initiation, age at first pregnancy, and experience of sexual violence in the adolescent population visiting a primary health unit in Brazil. We recruited 201 female adolescents who visited the gynecology outpatient clinic of...
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Research on Multi-Time-Delay Gene Regulation Network Based on Fuzzy Label Propagation: In view of time delay existing in gene regulation, by using the analysis idea and methods of complex network, this paper proposes a multi-time-delay gene regulation network analysis method based on the fuzzy label propagation. The algorithm takes the relative change trend coefficient, the correlation coefficient, and the mutual information as the similarity measurement indexes for the gene pair, fully reflecting...
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Long Noncoding RNA Lnc-TLN2-4:1 Suppresses Gastric Cancer Metastasis and Is Associated with Patient Survival: Gastric cancer (GC) is one of the most common malignancies worldwide, and the tumor metastasis leads to poor outcomes of GC patients. Long noncoding RNAs (lncRNAs) have emerged as new regulatory molecules that play a crucial role in tumor metastasis. However, the biological function and underlying mechanism of numerous lncRNAs in GC metastasis remain largely unclear. Here, we report a novel...
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Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries: Coronary artery disease (CAD) is a known potential complication of thoracic radiation treatment that typically affects the proximal segments of the coronary arteries, requiring coronary artery bypass grafting (CABG). We present a case of acute coronary syndrome occurring in a 57-year-old man with prior thoracic radiation therapy following resection of a chest wall chondrosarcoma. Coronary angiogram...
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A prospective multicentre REFCOR study of 470 cases of head and neck Adenoid cystic carcinoma: epidemiology and prognostic factors: Adenoid cystic carcinoma (ACC) accounts for 1% of malignant head and neck tumours [1] and 10% of salivary glands malignant tumours. The main objective of our study is to investigate the prognostic factors influencing the event-free survival (EFS) of patients with ACC.Article in PressA prospective multicentre REFCOR study of 470 cases of head and neck Adenoid cystic carcinoma:...
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British Journal of Cancer - Tumour-agnostic drugs in paediatric cancersBritish Journal of Cancer, Published online: 12 March 2020; doi:10.1038/s41416-020-0770-5Tumour-agnostic drugs in paediatric cancersBritish Journal of Cancer - Issue - nature.com science feeds3hTwo first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumoursBritish Journal of Cancer, Published online: 12 March 2020; doi:10.1038/s41416-020-0774-1Two...
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Latest Results for Aging Clinical and Experimental Research,Safety and tolerability of 6-month supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink in sarcopenic older adultsAbstract Aims Safety and tolerability of prolonged supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink (WP-MND) was evaluated in sarcopenic older adults. Methods A 13-week double-blinded, randomized, isocaloric placebo-controlled trial...
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Indian Journal of Anaesthesia : The 2019 novel corona virus outbreak – An institutional guidelineVarun SureshIndian Journal of Anaesthesia 2020 64(3):242-243Indian Journal of Anaesthesia : 2014 - 58(6)3hSevere Dengue: Lessons learnt from an observational studySubhash K TodiIndian Journal of Anaesthesia 2020 64(3):169-170Indian Journal of Anaesthesia : 2014 - 58(6)3hAdvances in vaporisation: A narrative reviewPankaj Kundra, Shreya Goswami, Aruna ParameswariIndian Journal of Anaesthesia 2020 64(3):171-180...
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Latest Results for European Archives of Oto-Rhino-Laryngology,,The first description of cholesteatoma by HippocrateAbstract Introduction Although otolaryngology became a subspecialty only since the middle of the nineteenth century, many diseases of ENT system, their clinical symptoms, universality and potential seriousness have been described since over 3000 years ago. Texts of the medical school of Cos and its founder Hippocrates (460–370 BC) collected in the Corpus Hippocraticum also contain multiple...
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A stepwise titration protocol for oral appliance therapy in positional obstructive sleep apnea patients: proof of concept: AbstractPurposeIn patients with positional obstructive sleep apnea (POSA), oral appliance therapy (OAT) is among the first-line treatments. The aim of this study was to evaluate the effects of a new standardized stepwise titration protocol for OAT in a group of patients with POSA.MethodsThis was an observational intervention trial. Patients who were previously randomized to the...
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Effectiveness of sleep surgery versus a mandibular advancement device for obstructive sleep apnea in terms of nocturnal cardiac autonomic activity: AbstractPurposeSleep surgery and mandibular advancement devices (MAD) are treatments for obstructive sleep apnea (OSA), but their comparative efficacy remains unclear. We compared their efficacy using various parameters.MethodsSubjects treated for OSA with sleep surgery or MAD (n = 30/group)—matched for sex, body mass index (BMI), and baseline apnea–hypopnea...
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Tissue Engineering Part A - Table of Contents,Alginate Hydrogels for In Vivo Bone Regeneration: The Immune Competence of the Animal Model MattersTissue Engineering Part A, Ahead of Print.Tissue Engineering Part A - Table of Contents1hMark above section as read Cancer Biotherapy & Radiopharmaceuticals - Table of ContentsMortal Obligate RNA Transcript Inhibits Cancer Cell Invasion and Migration in Lung Adenocarcinoma by Downregulating miRNA-223Cancer Biotherapy and Radiopharmaceuticals, Ahead...
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Coccidioidomycosis in Children and Adolescents: an Update: AbstractPurpose of ReviewCoccidioidomycosis is a systemic fungal infection endemic in Southwestern United States, Northern Mexico, Central and South America. Coccidioidal infection is not well characterized in pediatric population; but due to an increasing incidence in this age group, a special interest had surged to further describe clinical findings, treatment and clinical course of pediatric patients with coccidioidomycosis.Recent FindingsIn...
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Viruses, Vol. 12, Pages 300: Successful Infection of Domestic Pigs by Ingestion of the European Soft Tick O. Erraticus That Fed on African Swine Fever Virus Infected PigViruses, Vol. 12, Pages 300: Successful Infection of Domestic Pigs by Ingestion of the European Soft Tick O. Erraticus That Fed on African Swine Fever Virus Infected Pig Viruses doi: 10.3390/v12030300 Authors: Pereira De Oliveira Hutet Duhayon Guionnet Paboeuf Vial Le Potier African swine fever is a highly lethal hemorrhagic fever...
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Nutrients, Vol. 12, Pages 738: Development of a Danish Adapted Healthy Plant-Based Diet Based on the EAT-Lancet Reference DietNutrients, Vol. 12, Pages 738: Development of a Danish Adapted Healthy Plant-Based Diet Based on the EAT-Lancet Reference Diet Nutrients doi: 10.3390/nu12030738 Authors: Anne D. Lassen Lene M. Christensen Ellen Trolle Plant-based diets have been linked to both health benefits and a lower climate impact. However, plant-based diets may represent both healthy and unhealthy dietary...
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Molecules, Vol. 25, Pages 1273: Design and Development of Spray-Dried Microsystems to Improve Technological and Functional Properties of Bioactive Compounds from Hazelnut ShellsMolecules, Vol. 25, Pages 1273: Design and Development of Spray-Dried Microsystems to Improve Technological and Functional Properties of Bioactive Compounds from Hazelnut Shells Molecules doi: 10.3390/molecules25061273 Authors: Esposito Mencherini Del Gaudio Auriemma Franceschelli Picerno Aquino Sansone An extract obtained...
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International Journal of Molecular Sciences,IJMS, Vol. 21, Pages 1915: Electrohypersensitivity as a Newly Identified and Characterized Neurologic Pathological Disorder: How to Diagnose, Treat, and Prevent ItIJMS, Vol. 21, Pages 1915: Electrohypersensitivity as a Newly Identified and Characterized Neurologic Pathological Disorder: How to Diagnose, Treat, and Prevent It International Journal of Molecular Sciences doi: 10.3390/ijms21061915 Authors: Belpomme Irigaray Since 2009, we built up a database...
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Diversity, Vol. 12, Pages 97: Taxonomy, Evolution, and Biogeography of the Rhodniini Tribe (Hemiptera: Reduviidae)Diversity, Vol. 12, Pages 97: Taxonomy, Evolution, and Biogeography of the Rhodniini Tribe (Hemiptera: Reduviidae) Diversity doi: 10.3390/d12030097 Authors: Hernández Aristeu da Rosa Vallejo Guhl Ramírez The Triatominae subfamily includes 151 extant and three fossil species. Several species can transmit the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease, significantly...
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Antibiotics, Vol. 9, Pages 118: Antibiotic Resistance in Marine Microbial Communities Proximal to a Florida Sewage Outfall SystemAntibiotics, Vol. 9, Pages 118: Antibiotic Resistance in Marine Microbial Communities Proximal to a Florida Sewage Outfall System Antibiotics doi: 10.3390/antibiotics9030118 Authors: Griffin Banks Gregg Shedler Walker Water samples were collected at several wastewater treatment plants in southeast Florida, and water and sediment samples were collected along and around one...
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pubmed: frontiers in neurosc...Simultaneous Electrophysiology and Fiber Photometry in Freely Behaving Mice.Related ArticlesSimultaneous Electrophysiology and Fiber Photometry in Freely Behaving Mice. Front Neurosci. 2020;14:148 Authors: Patel AA, McAlinden N, Mathieson K, Sakata S Abstract In vivo electrophysiology is the gold standard technique used to investigate sub-second neural dynamics in freely behaving animals. However, monitoring cell-type-specific population activity is not a trivial task....
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Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review: Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy,...
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pubmed: "world neurosurg"[jo...Conservative versus surgical treatment for odontoid fracture: Is the surgical treatment harmful? Systematic review and meta-analysis.Related ArticlesConservative versus surgical treatment for odontoid fracture: Is the surgical treatment harmful? Systematic review and meta-analysis. World Neurosurg. 2020 Mar 06;: Authors: Pommier B, Ollier E, Pelletier JB, Castel X, Vassal F, Tetard MC Abstract BACKGROUND: Odontoid fracture is a common injury especially in elderly people....
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Head and NeckConsortium of Otolaryngology Journal Editors: Collegiality and Contributions.Related ArticlesConsortium of Otolaryngology Journal Editors: Collegiality and Contributions. Clin Otolaryngol. 2020 Mar 09;: Authors: Tysome JR Abstract There is a new tradition in the otolaryngology publishing community that is unique to our specialty, so far as we know. Editors-in-Chief of otolaryngology journals in the United States, and intermittently some of our international colleagues such as the Editor...
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PeerJ Computer ScienceApplication of artificially intelligent systems for the identification of discrete fossiliferous levelsThe separation of discrete fossiliferous levels within an archaeological or paleontological site with no clear stratigraphic horizons has historically been carried out using qualitative approaches, relying on two-dimensional transversal and longitudinal projection planes. Analyses of this type, however, can often be conditioned by subjectivity based on the perspective of the...
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OncologyImmunotherapy in Malignant Pleural Mesothelioma.Related ArticlesImmunotherapy in Malignant Pleural Mesothelioma. Front Oncol. 2020;10:187 Authors: de Gooijer CJ, Borm FJ, Scherpereel A, Baas P Abstract The only registered systemic treatment for malignant pleural mesothelioma (MPM) is platinum based chemotherapy combined with pemetrexed, with or without bevacizumab. Immunotherapy did seem active in small phase II trials. In this review, we will highlight the most important immunotherapy-based...
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[Cervial vestibular-evoked myogenic potential induced by galvanic vestibular stimulation in normal people].: Related Articles[Cervial vestibular-evoked myogenic potential induced by galvanic vestibular stimulation in normal people].Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan;34(1):57-60Authors: Cheng Y, Zhang YZ, Han YQ, Ma WJ, Yang H, Zhao J, Chen F, Zhang Q, Xu MAbstract Objective:To establish a new method for detecting vestibular function by testing cervical vestibular-evoked...
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World NeurosurgeryArterial Supply of the Thalamus: A Comprehensive ReviewPublication date: May 2020Source: World Neurosurgery, Volume 137Author(s): Stephen Bordes, Cassidy Werner, Mansour Mathkour, Erin McCormack, Joe Iwanaga, Marios Loukas, Markus Lammle, Aaron S. Dumont, R. Shane TubbsWorld NeurosurgeryWed Mar 11, 2020 13:44The Retroverted Dens: A Review of its Anatomy, Terminology, and Clinical SignificancePublication date: May 2020Source: World Neurosurgery, Volume 137Author(s): Basem Ishak,...
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European Journal of Nuclear Medicine and Molecular ImagingDynamic PET/CT imaging of 18 F-(2 S , 4 R )4-fluoroglutamine in healthy volunteers and oncological patientsAbstract Purpose The purpose of this study was to compare dynamic 18F-FGln PET/CT images of healthy subjects and cancer patients and explore the best imaging phase for different cancers. Methods Thirteen healthy volunteers and 31 cancer patients separately underwent 18F-FGln and 18F-FDG PET/CT scans within 1 week. The distributions of...
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Hair cortisol analyses in different mammal species: choosing the wrong assay may lead to erroneous results.: Related ArticlesHair cortisol analyses in different mammal species: choosing the wrong assay may lead to erroneous results.Conserv Physiol. 2020;8(1):coaa009Authors: Jewgenow K, Azevedo A, Albrecht M, Kirschbaum C, Dehnhard MAbstract Wild animals are faced with a broad range of environmental stressors and research is needed to better understand their effect on populations. Hormone...
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1 Therapeutic Targeting of the IGF AxisOsher E and Macaulay VM. Cells 2019 - Review. PMID 31416218 Free PMC article.Finally, we summarize grounds for cautious optimism for ongoing and future studies of IGF blockade in cancer and non-malignant disorders including thyroid eye disease and aging....Cite AMA MLA APA NLM Share2 Second-line treatments in children with immune thrombocytopenia:...
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MiR-324-5p/PTPRD/CEBPD axis promotes papillary thyroid carcinoma progression via microenvironment alteration.: Related ArticlesMiR-324-5p/PTPRD/CEBPD axis promotes papillary thyroid carcinoma progression via microenvironment alteration.Cancer Biol Ther. 2020 Mar 10;:1-11Authors: Yang Y, Xia S, Zhang L, Wang W, Chen L, Zhan WAbstract MiR-324-5p is overexpressed in papillary thyroid carcinoma (PTC) with lymph node metastasis and promotes malignant phenotypes of KTC-1 cell line. However, the...
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Nasal Airway Resistance and Latent Lower Airway Involvement in Allergic Rhinitis.Iyer A1, Athavale A2.Author informationAbstractINTRODUCTION:Allergic rhinitis (AR) and asthma are closely linked atopic conditions, often termed as one airway one disease. Nasal airflow obstruction is a cardinal symptom of AR and objective assessment of resistance to nasal airflow in rhinitis can be measured by active anterior rhinomanometry. This study was aimed at correlating the degree of resistance to nasal airflow...
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1.PLoS One. 2020 Mar 10;15(3):e0229355. doi: 10.1371/journal.pone.0229355. eCollection 2020.Genetic diversity and evolutionary analysis of human respirovirus type 3 strains isolated in Kenya using complete hemagglutinin-neuraminidase (HN) gene.Elusah J1, Bulimo WD2,3, Opanda SM2, Symekher SL4, Wamunyokoli F1.Author informationAbstractHuman respirovirus type 3 (HRV3) is a leading etiology of lower respiratory tract infections in young children and ranks only second to the human respiratory syncytial...
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HNOTherapieentscheidungen in der OnkologieZusammenfassung Hintergrund Die Diagnose einer Krebserkrankung geht immer mit einer Lebensbedrohung einher und fordert deshalb besonders viel vom Entscheider. Für Patienten bedeutet dies, Entscheidungen unter hoher emotionaler Belastung zu fällen. Auf der anderen Seite können medizinische Fakten limitierend auf die Entscheidungsfreiheit einwirken. In der Interaktion mit dem Patienten bedeutet dies für das ärztliche Handeln häufig eine...HNOWed Mar 11, 2020...
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1.Proc Natl Acad Sci U S A. 2020 Mar 9. pii: 201912375. doi: 10.1073/pnas.1912375117. [Epub ahead of print]DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes.Basu S1, Barad M1, Yadav D1, Nandy A1, Mukherjee B2, Sarkar J3, Chakrabarti P3, Mukhopadhyay S2, Biswas D4.Author informationAbstractAmong all of the Super Elongation Complex (SEC) components, ELL1 (also known as ELL) is the only bona fide elongation factor that directly stimulates...
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ANZ Journal of SurgeryNational Surgical Quality Improvement Program risk calculator validity in South Australian laryngectomy patientsThe America College of Surgeons' National Surgical Quality Improvement Program risk calculator was developed to calculate patient's 30‐day post‐operative risks to provide surgeons with information to guide preoperative decision‐making. The America College of Surgeons' National Surgical Quality Improvement Program risk calculator effectively predicted post‐operative...
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International Journal of CancerAdefovir dipivoxil induces DNA replication stress and augments ATR inhibitor related cytotoxicityReplication stress is a common feature of cancer cells. Ataxia Telangiectasia Mutated (ATM) and Rad3 related (ATR) signalling, a DNA damage repair (DDR) pathway, is activated by regions of single‐stranded DNA (ssDNA) that can arise during replication stress. ATR delays cell cycle progression and prevents DNA replication fork collapse, which prohibits cell death and promotes...
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Clinical & Experimental AllergyAirway hyperresponsiveness, remodeling and inflammation in infants with wheezeAbstract Background The relationship of airway hyperresponsiveness to airway remodeling and inflammation in infants with wheeze is unclear. Objective To investigate airway hyperresponsiveness, remodeling and inflammation in infants with wheeze and troublesome breathing. Methods Inclusion criteria: full‐term, 3‐23 months of age; doctor diagnosed wheeze and persistent recurrent troublesome...
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ParasiteEpidemiology and hypothetical transmission cycles of Trichinella infections in the Greater Kruger National Park of South Africa: an example of host-parasite interactions in an environment with minimal human interactionsAuthors: Louis J. La Grange and Samson Mukaratirwa.Parasite Vol. 27 , page 13Published online: 12/03/2020 Keywords: Trichinella ; Kruger National Park ; South Africa.Parasite02:00Mark above section as read Popular ScienceFrom the death cap to the alcohol inky: seven poisonous...
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bioRxiv Subject Collection: Evolutionary BiologyAncient and modern genomes reveal microsatellites maintain a dynamic equilibrium through deep time [NEW RESULTS]Microsatellites are widely used in population genetics, but their evolutionary dynamics remain poorly understood. It is unclear whether microsatellite loci drift in length over time. We identify more than 27 million microsatellites using a novel and unique dataset of modern and ancient Adelie penguin genomes along with data from 63 published...
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World Journal of Emergency Surgery - Latest ArticlesComparison between simple triage and rapid treatment and Taiwan Triage and Acuity Scale for the emergency department triage of victims following an earthquake-related mass casualty incident: a retrospective cohort studyTriage plays a crucial role in the emergency department (ED) management of mass casualty incidents (MCIs) when resources are limited. This study aimed to compare the performance of simple triage and rapid trea...World Journal of...
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