Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles

Although gut microbiota plays critical roles in regulating immunological responses in intestines, the potential roles of lung microbiota in local immune responses are largely unknown. Yang et al. demonstrate that dysregulated lung commensal bacteria drive interleukin-17B production to promote pulmonary inflammation and fibrosis through their outer membrane vesicles.

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