Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue

Acute seizure models are important for studying the mechanisms underlying epileptiform events. Furthermore, the ability to generate epileptiform events on-demand provides a highly efficient method to study the exact sequence of events underlying their initiation. Here, we describe the acute 4-aminopyridine cortical seizure models established in mouse and human tissue.

http://bit.ly/2FN1ryb