Timing of Local Therapy Impacts Survival in Ewing Sarcoma

The optimal timing of local therapy in Ewing sarcoma patients is unclear. We queried the National Cancer Database for localized Ewing sarcoma patients treated with chemotherapy and local therapy and analyzed overall survival by time to local therapy following chemotherapy initiation. Delayed time to local therapy > 16 weeks after chemotherapy initiation was independently associated with worse survival in patients receiving radiotherapy with localized Ewing sarcoma.

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