The Effectiveness and Prognostic Factors of CT-guided Radioactive Iodine-125 Seed Implantation for the Treatment of Recurrent Head and Neck Cancer after External Beam Radiotherapy

In this study, we investigated the efficacy and safety of I-125 seed implantation for the treatment of recurrent head and neck cancer after EBRT. The results indicated I-125 seed implantation is an acceptable salvage therapy, with 1-year local control rate of 40.6% and 5-year local control rate of 26.6%. G3 and G4 toxicity was 7.9% and 2%, respectively. The independent factors for local control rate included pathological type, lesion volume, D90, and short-term efficacy.

https://ift.tt/2qoHfKb