Efficacy of low-temperature plasma activated gas disinfection against biofilm on contaminated GI endoscope channels

It has been increasingly recognized that the safety of gastrointestinal endoscopes needs to be improved by addressing the small margin of safety of high-level disinfectants (HLD), and the failure of HLD to clear multi-drug resistant organisms and biofilms. There is also an unmet need for effective low-temperature sterilization techniques that have a clear pathway for FDA clearance. Here, we report the results of our investigation of a novel argon plasma-activated gas (PAG) for disinfection and potentially sterilization of biofilm-contaminated endoscopic channels.

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