PulmCrit Wee – Metabolic resuscitation for severe pneumonia?

Metabolic resuscitation for sepsis is currently quite controversial.  Marik et al. published a before-after study in 2017 describing the combination of hydrocortisone, ascorbate, and thiamine for septic shock. That study incited a media storm of surprising intensity.  Currently, several multi-center RCTs are underway to answer this question more definitively.  In the interim, some additional before/after trials may emerge.  These studies likely won't answer the question, but they may provide us with some clues about whether metabolic resuscitation is on the right track.

EMCrit Project by Josh Farkas.

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