Molecular Imaging in Gastroenterology: a route for personalized endoscopy

With the rapid expansion and diversification of the repertoire of biological agents utilized in inflammatory bowel diseases and cancer and the increase in oncological patients in gastroenterology, visualization of single receptor or molecular target expression and the subsequent initiation of expression tailored therapy are gaining increasing attention. Through the combination of utilizing fluorescently labelled probes with high specificity towards defined molecular targets and their subsequent detection and visualisation with endoscopic devices, molecular imaging is a new emerging field focussing on the receptor expression within the mucosa on a cellular level rather than on macroscopic changes.

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