Fatigue after aneurysmal subarachnoid hemorrhage is highly prevalent in the first year post onset and related to low physical fitness: A longitudinal study

Objective To investigate whether low physical fitness and inactive and sedentary lifestyles play a role in the severity of fatigue in patients with aneurysmal subarachnoid hemorrhage (a-SAH). Design Prospective one-year follow-up study, including a total of 52 patients with a-SAH. Outcome measures included the Fatigue Severity Scale -score, peak oxygen uptake (V[Combining Dot Above]O2peak), isokinetic knee muscle strength (peak torque), physical activity (%24h period) and sedentary behavior (% waking hours), and were evaluated at six and twelve months post onset. Results Fatigue was highly prevalent in the first year, and reported by 48% of the patients at six months and by 52% at twelve months post a-SAH. Fatigue was associated with the knee extension (p

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