A prospective comparison of computerized-tomography (CT) based with trans-rectal-ultrasonography (TRUS) assistance and magnetic-resonance imaging (MRI) based target-volume definition during image guided adaptive brachytherapy for cervical cancers

Target volume definition and delineation (high risk) at the time of brachytherapy (BT) is an important step in image guided adaptive brachytherapy for cervical cancers. We present the first prospective study comparing CT-based target delineation with incorporation of trans-rectal ultrasonography at BT and gold standard approach of MR-based target delineation and report comparable results. These findings have a potential impact on brachytherapy practice for cervical cancers across the globe.

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