More Realistic Estimation of Time to ESRD in Children

It is the job of the pediatric nephrologist to slow the progression of chronic kidney disease (CKD) and provide realistic estimates for the time to end-stage kidney disease. On average, estimated glomerular filtration rate (eGFR) decreases by ∼4.0mL/min/1.73m2 per year in children with CKD.1 This can be improved with a programmatic multidisciplinary approach, potentially to as little as 0.5mL/min/1.73m2 per year.1,2 Based on the very large Annual Health Exam Participants in Japan study, the attrition of eGFR is 0.36mL/min/1.73m2 per year in healthy adult individuals and presumably the same in children.

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