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Τρίτη 22 Μαΐου 2018

Goldilocks in the NICU—can oxygen be titrated “just right?”

Oxygen is the most commonly used "drug" for preterm infants, and recent large clinical trials highlight the need for careful titration within a narrow therapeutic window. In particular, lower achieved oxygen saturations are associated with increased mortality in extremely preterm infants, possibly due to more time spent in extreme hypoxemia. Automated systems that adjust the inspired oxygen based on the detected O2 saturation are a timely innovation that should improve the ease and precision of maintaining oxygenation within the desired range.

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