Are qSOFA Criteria Better Than the Systemic Inflammatory Response Syndrome Criteria for Diagnosing Sepsis and Predicting Inhospital Mortality?

Authors included 10 studies with 229,480 patients from 4,022 citations retrieved from their initial literature search. One study conducted among ICU patients accounted for 80.6% of included patients (184,875).2 Eight studies evaluated patients in the emergency department, whereas 2 studies evaluated patients at ICU admission. Studies used different criteria for diagnosis of infection in sepsis: 4 used clinically presumed or suspected infection; 1 considered suspicion of infection resulting in antibiotics; 2 considered clinical suspicion resulting in cultures and antibiotics; 1 used diagnosis of sepsis at admission; 1 considered at least 2 criteria of systemic inflammatory response syndrome criteria, SOFA, or qSOFA; and 1 used the International Classification of Diseases, Ninth Revision coding for infection.

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