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Τετάρτη 18 Απριλίου 2018

18F-EF5 PET-based Imageable Hypoxia Predicts Local Recurrence in Tumors Treated with Highly Conformal Radiation Therapy

18F-pentafluorinated etanidazole (18F-EF5) PET is a promising hypoxia imaging modality. We enrolled 28 patients undergoing highly conformal radiation therapy for localized lung and other tumors on a prospective clinical study to characterize the prevalence of imageable hypoxia by EF5-PET and its relationship to local tumor control after treatment. 43% of tumors demonstrated imageable hypoxia by EF5-PET, and the local tumor recurrence rate was higher in tumors with imageable hypoxia.

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