Comparing Like with Like When Reporting Neurodevelopmental Outcomes after Preterm Birth

For nearly 20 years, investigators of randomized clinical trials in neonatology have used a primary endpoint of death or survival with impairment in at least 1 of the following domains: cognition, motor function, hearing, and vision.1-3 This composite outcome of death or neurodevelopmental impairment (NDI) has also gained popularity for observational neonatal research. However, as Haslam et al from the Canadian Neonatal Follow-up Network describe in this volume of The Journal, NDI has been defined in many different ways.

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