Are Corticosteroids Superior to Nonsteroidal Anti-inflammatory Drugs in the Treatment of Acute Gout?

The search identified 529 references; 6 trials evaluating 817 patients met inclusion criteria. The overall risk of bias was low in these trials, whereas the quality of the evidence was rated as low to moderate according to GRADE criteria. The meta-analysis demonstrated no difference between corticosteroids and nonsteroidal anti-inflammatory drugs for the following outcomes: short-term pain relief (<7 days), long-term pain relief (>7 days), time to resolution of pain, and requirement for additional analgesics (Table 1).

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