Transposition of Tn1213 encoding the PER-1 Extended Spectrum {beta}-lactamase [PublishAheadOfPrint]

PER-1 is an extended-spectrum β-lactamase that is encoded by a gene located into the composite transposon Tn1213 made by two distinct insertion sequences, namely ISPa12 and ISPa13. In vitro mobilization performed in Escherichia coli shows that Tn1213 is functional and is able to mobilize the bla_PER-1 gene although at a very low frequency (ca 1x10^-9).

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