Superior Hypertension Management in Pediatric Kidney Transplant Patients After Native Nephrectomy.

Background: Native nephrectomy in pediatric kidney transplant recipients is performed for multiple indications. Posttransplant hypertension requiring medical management is common and the effect of native nephrectomy on posttransplant hypertension is poorly studied. Our aim is to evaluate the impact of native nephrectomy on posttransplant hypertension. Methods: 136 consecutive pediatric kidney transplant recipients from 2007 to 2012 were studied at a single institution and divided into 2 groups: no nephrectomy and native nephrectomy (unilateral and bilateral nephrectomy). Antihypertensive medication use was evaluated prior to nephrectomy/transplant, at discharge from transplant and at 1-, 3- and 5-years posttransplant. Results: In a bivariate analysis, nephrectomy was associated with a significant reduction in the percentage of patients requiring antihypertensive medication at the time of discharge (27.3%) and 1 year posttransplant (10.7%) as compared to patients without nephrectomy (71.7%, and 50%, respectively, p

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