Essential Insights into Lipid Membrane Organization from Essential Fatty Acids

Cell membrane structure and dynamics are key to maintaining a properly functioning cell, and lipids have a dominant role in determining the organization of cell membranes. Since 1972, when the fluid-mosaic model was published, awareness has been growing that the "mosaic" aspect of membrane structure is as important as the "fluid" aspect (1). Integral membrane proteins, particularly those that link to the cytoskeleton and those that can form signaling platforms, certainly determine aspects of the mosaic.

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