Paip1 affects breast cancer cell growth and represents a novel prognostic biomarker

Polyadenylate-binding protein-interacting protein 1 (Paip1) regulates translational initiation. Increasing evidence suggests that Paip1 plays important roles in cancer development and progression. This study explored the role of Paip1 in breast cancer progression and evaluated its prognostic value. The cellular location of Paip1 protein was determined using immunofluorescence (IF). Then, Paip1 protein expression was evaluated by immunohistochemical (IHC) staining in 119 breast cancers and 40 normal breast tissues.

http://ift.tt/2kBQ00f