Cell-Membrane Engineering: Engineering Cell Surface Function with DNA Origami (Adv. Mater. 46/2017)

DNA-origami nanodevices are embedded on the membrane of two cells by Jonathan W. Song, Carlos E. Castro, and co-workers in article number 1703632. The devices are anchored to the cell via a DNA base-pairing attachment to a cholesterol-labeled DNA strand embedded in the membrane. The two pairs of nanostructures (shown here on the right) mediate adhesion between the cells via a sequence-specific DNA binding interaction.

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