2D MoS2 Nanostructures for Biomedical Applications

Abstract

MoS₂ nanosheets, a typical kind of layered transition metal dichalcogenides with the 2D structure and many unique physical and chemical properties, have attracted a lot of research interests in various fields. Typically, MoS₂ nanosheets present similarities to graphene in terms of their large surface area and strong absorbance in near-infrared region, which in combination with their easily functionalized surface make them promising nanoplatforms in biomedical applications. Herein, the progress of MoS₂ nanosheets and their composites in the area of nanomedicine, with the emphasis on their synthesis and modification strategies, their biomedical applications in biosensing, imaging and therapy, as well as evaluations of their in vivo behaviors and toxicology profiles are summarized. Finally, the challenges and opportunities of applying MoS₂-based nanomaterials in the biomedicine areas will be discussed.

Two-dimensional MoS₂ nanostructures have received tremendous attention from many fields including biomedicine. This review article summarizes different synthesis and modification strategies of those nanomaterials, their applications in biosensing, imaging, and cancer therapy, as well as the evaluations of their in vivo behaviors and toxicology profiles. The challenges and opportunities of applying MoS₂-based nanomaterials in the biomedicine areas are then discussed.

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