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Τετάρτη 27 Σεπτεμβρίου 2017

Prognostic implication of NQO1 overexpression in hepatocellular carcinoma

To explore the role of NQO1 overexpression for prognostic implication in HCC, NQO1 mRNA levels were detected in HCC fresh tissue samples of HCC and non tumor tissues, respectively. 156 cases of HCC meeting strict follow-up criteria were selected for immunohistochemical staining of NQO1 protein. Correlations between NQO1 overexpression and clinicopathological features of HCC were evaluated using Chi-square tests, survival rates were calculated using the Kaplan–Meier method, and the relationship between prognostic factors and patient 5-year survival was analyzed using Cox proportional hazard analysis.

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