Long-term outcomes for cryotherapy in Barrett’s esophagus with high-grade dysplasia: just cracking the ice

Although the progression from Barrett's esophagus (BE) to esophageal adenocarcinoma (EAC) is well established, it has been increasingly recognized that there is an overall low frequency of this progression in the absence of dysplasia.1 Indeed, multiple, large population–based cohorts have demonstrated that the annual incidence of EAC in BE without dysplasia is 0.1% to 0.3% per year.1,2 In sharp contrast, the annual risk of progression to EAC in patients with high-grade dysplasia (HGD) is estimated at 6%.

http://ift.tt/2ycR9Bs