P384 The role of sleep spindles in overnight verbal memory consolidation in temporal lobe epilepsy patients

Declarative memory performance and hippocampal functioning are highly associated. Learning induced memory consolidation results in an increased coupling between mesial temporal lobe, thalamus and frontal areas during sleep, resulting in the increase of sleep spindles and slow wave sleep. Our aim was to investigate the modulatory effect of learning on sleep spindles in temporal lobe epilepsy (TLE) patients and to see whether the association between declarative memory consolidation and sleep parameters are altered.

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