MicroRNAs, promising biomarkers in the diagnosis of Xp11 translocation RCC—reply

We read with great interest the Letter to the Editor entitled "MicroRNAs, promising biomarkers in diagnosis of Xp11 translocation RCC" by Li et al, in which the authors provide a synopsis of the microRNA expression profiles associated with distinct renal cell carcinoma (RCC) subtypes in response to our recent paper on Xp11 RCC [1]. This letter further underscores the importance of recognizing the molecular underpinnings of RCC subtypes to advance our knowledge of this disease, provide the rationale for improved RCC molecular classification, and possibly foster the development of targeted therapeutic interventions.

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