Imaging Findings within the first 12 months of Hepatocellular Carcinoma treated with Stereotactic Body Radiation Therapy (SBRT)

In the absence of increasing size, persistent arterial hyperenhancement with washout can occur within the first 12 months post-SBRT in successfully treated HCCs, and should not be confused with residual tumor. Liver parenchyma adjacent to the treated lesion showed inflammation followed by fibrosis, without significant change in hepatic function. Until a radiological signature of tumor control is determined, freedom from local progression appears to be the best measure of HCC control after SBRT.

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