Subsquamous intestinal metaplasia is common in treatment-naïve Barrett’s esophagus

Barrett's intestinal metaplasia may extent beneath normal squamous epithelium at the squamocolumnar junction (SCJ) and therefore escape surveillance biopsies. The prevalence of subsquamous intestinal metaplasia (SSIM) in patients undergoing Barrett's esophagus (BE) surveillance is unknown. Our aim was to examine the prevalence and distribution of SSIM proximal to the SCJ in patients undergoing BE surveillance.

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