Is Antiplatelet Therapy an Independent Risk Factor for Traumatic Intracranial Hemorrhage in Patients With Mild Traumatic Brain Injury?

A total of 3,193 separate articles were identified by the searches; 28 were selected for closer review and 10 articles were included in the final review, 1 retrospective case-control study, 7 retrospective cohort studies, and 2 prospective cohort studies, all from January 2003 to September 2015. Pooled data resulted in 2,966 patients with 553 traumatic intracranial hemorrhages (19%) in the combined antiplatelet group and 18,281 total patients with 1,422 (8%) traumatic intracranial hemorrhages in the combined control group.

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