T-Cell-Mediated Cross-Protective Immunity.

T-Cell-Mediated Cross-Protective Immunity.

Methods Mol Biol. 2017;1625:295-312

Authors: Khanna N, Stuehler C

Abstract
Human invasive fungal infections are caused by different mold and yeast species. Hence, cross-reactive T cells that recognize conserved epitopes of various fungal pathogens are of special interest for vaccination protocols or adoptive T cell transfer. Here, we describe an ELISpot-based method to test cross-reactivity of T cell lines or clones to different molds and yeasts.

PMID: 28584998 [PubMed - in process]

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