Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

Haas et al. identify integrin α7 as a functional marker of glioblastoma stem cells by screening a monoclonal antibody library generated against primary glioblastoma (GBM) cells. Functional experiments in culture and in vivo show that the targeting of integrin α7 has potential as a therapeutic avenue for treating this aggressive disease.

http://ift.tt/2sHrRZp