Jadhav et al. identify an active enhancer signature that distinguishes Lgr5+ intestinal stem cells (ISCs) from Bmi1GFP+ and other secretory cells, including CD69+CD274+ goblet cell precursors. These specialized cells dedifferentiate into Lgr5+ ISCs in response to stem cell attrition, which is accompanied by dynamic rearrangements in open chromatin signatures.
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Πέμπτη 22 Ιουνίου 2017
Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells
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This protocol presents an in vitro live-imaging phagocytosis assay to measure the phagocytic capacity of astrocytes. Purified rat astrocyt...
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Measuring alterations in metabolic rates is central to understanding the progression of various diseases and aging. Here, we present a nov...
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Association française pour l'étude du cancer [Imatinib in the treatment of chronic myeloid leukemia in Morocco]. Related Articles [Im...
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