Regional Differences in the Associations Between Prescribed Dialysate Sodium Concentration and Interdialytic Weight Gain in the Dialysis Outcomes and Practice Patterns Study

Higher dialysate sodium (DNa) prescription levels are associated with thirst and interdialytic weight gain (IDWG, reviewed in1). A recent analysis from the United States found that measured DNa may be considerably higher than prescribed DNa,2 contrasting the results of another study from Austria/Europe.3 In the US study, the magnitude of the differences (prescribed minus measured DNa) ranged from −13 to +6 mEq/L, and measured DNa concentrations were ±2 mEq/L of prescribed DNa concentrations in 57.0% of treatments.

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