In Reply to Peñagarícano

To the Editor: We thank the author for his interest in our publication (1, 2) and appreciate his "benign" comments. Please allow us to make some further remarks regarding this important topic. The author of the letter pointed out that there is a high acceptance of radiation therapy (RT) for benign diseases in Central Europe and very low acceptance in the Anglo-American countries (3). In fact, this may be due more to tradition than to evidence-based medicine (EBM). Clearly in Great Britain and the United States it refers to former bad experience with radiation treatment of nonmalignant diseases (4) and 3 randomized clinical trials showing no positive effect of low-dose RT (5-7).

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