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Παρασκευή 30 Σεπτεμβρίου 2016

A typical case of a widespread metastatic breast carcinoma

Abstract

Cutaneous metastasis is an uncommon manifestation of visceral malignancy. Among all malignancies, the highest incidence of cutaneous metastasis is seen in breast cancer. Cutaneous metastasis can be the initial presentation of breast carcinoma. However, it usually presents a few months or years after the primary disease has been diagnosed and treated. Cutaneous metastases develop most commonly at the same time as internal metastases.3,8 The incidence of cutaneous metastases for all types of carcinomas ranges from 0.7% to 10.0%.3,5 A more recent meta-analysis demonstrated the overall incidence to be closer to 5.3%.4,5 We present herein a case of carcinoma breast in a 55-year-old female presenting initially with skin lesions on the chest wall. Further evaluation identified a bilateral breast mass with axillary metastasis and multiple nodules over the trunk and right thigh. There was also evidence of metastasis to the lungs, bilateral adrenals and mesenteric lymph nodes. FNAC of all the nodules revealed infiltrating duct carcinoma of the breast which was confirmed by excision biopsy.



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