The development of smart nanocarriers for the delivery of therapeutic drugs has experienced considerable expansion in recent decades, with the development of new medicines devoted to cancer treatment. In this respect a wide range of strategies can be developed by employing liposome nanocarriers with desired physico-chemical properties that, by exploiting a combination of a number of suitable soft interactions, can facilitate the transit through the biological barriers from the point of administration up to the site of drug action. As a result, the materials engineer has generated through the bottom up approach a variety of supramolecular nanocarriers for the encapsulation and controlled delivery of therapeutics which have revealed beneficial developments for stabilizing drug compounds, overcoming impediments to cellular and tissue uptake, and improving biodistribution of therapeutic compounds to target sites. Herein we present recent advances in liposome drug delivery by analyzing the main structural features of liposome nanocarriers which strongly influence their interaction in solution. More specifically, we will focus on the analysis of the relevant soft interactions involved in drug delivery processes which are responsible of main behaviour of soft nanocarriers in complex physiological fluids. Investigation of the interaction between liposomes at the molecular level can be considered an important platform for the modeling of the molecular recognition processes occurring between cells. Some relevant strategies to overcome the biological barriers during the drug delivery of the nanocarriers are presented which outline the main structure-properties relationships as well as their advantages (and drawbacks) in therapeutic and biomedical applications.
from #Medicine via ola Kala on Inoreader http://ift.tt/28Wtcot
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Ιουνίου
(946)
-
▼
Ιουν 25
(29)
- Predisposition or side effect of the duration: the...
- Interdependencies among Selected Pro-Inflammatory ...
- A Formulation Study of 5-Aminolevulinic Encapsulat...
- Thrombus Aspirated from Patients with ST-Elevation...
- IJMS, Vol. 17, Pages 1013: Hypoxia Potentiates Ana...
- IJMS, Vol. 17, Pages 1010: Synthesis, Characteriza...
- IJMS, Vol. 17, Pages 1012: Characterization and Ge...
- IJMS, Vol. 17, Pages 1011: Extraction, Characteriz...
- Foods, Vol. 5, Pages 47: A Rapid Colorimetric Meth...
- IJMS, Vol. 17, Pages 1011: Extraction, Characteriz...
- Polymers, Vol. 8, Pages 243: Enzymatic Synthesis o...
- IJMS, Vol. 17, Pages 1012: Characterization and Ge...
- Nanomaterials, Vol. 6, Pages 125: Soft Interaction...
- Sustainability, Vol. 8, Pages 598: A Socio-Institu...
- IJMS, Vol. 17, Pages 1010: Synthesis, Characteriza...
- Sensors, Vol. 16, Pages 971: Sensitivity Analysis ...
- Materials, Vol. 9, Pages 517: Physicochemical Char...
- Sensors, Vol. 16, Pages 972: An Approach to the Us...
- Molecules, Vol. 21, Pages 834: Analysis of Odorant...
- Nutrients, Vol. 8, Pages 393: Improvements in Cycl...
- Fluid-Structure Interaction and Structural Analyse...
- Fluid-structure interaction including volumetric c...
- Molecules, Vol. 21, Pages 832: Extraction Optimiza...
- Catalysts, Vol. 6, Pages 94: Brønsted Acid-Catalyz...
- Molecules, Vol. 21, Pages 827: Dual Behavior of Io...
- Metals, Vol. 6, Pages 143: Microwave Rapid Sinteri...
- IJMS, Vol. 17, Pages 1008: Computational Analysis ...
- Reciprocal Risk of Acute Kidney Injury and Acute R...
- In-Hospital Neurologic Complications in Adult Pati...
-
▼
Ιουν 25
(29)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Σάββατο 25 Ιουνίου 2016
Nanomaterials, Vol. 6, Pages 125: Soft Interaction in Liposome Nanocarriers for Therapeutic Drug Delivery
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
https://ift.tt/2MQ8Ai8
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.