Genome mining is an effective tool used to discover novel natural products from actinomycetes. Genome sequence analysis of Streptomyces sp. FJS31-2 revealed the presence of one putative type II polyketide gene cluster (ABX), which may correspond to type II polyketide products including BE-24566B and its chloro-derivatives. The addition of natural humus acid successfully activated the biosynthsis of the abx gene cluster. BE-24566B and its chloro-derivatives, named zunyimycin A, were also detected. The targeted deletion of the polyketide skeleton synthesis genes such as abxp, abxk, and abxs was performed in the wild strain to identify the gene cluster for BE-24566B biosynthesis.
from #Medicine via ola Kala on Inoreader http://ift.tt/1sWHwn8
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Μαΐου
(630)
-
▼
Μαΐ 30
(50)
- A Meta-Analysis of Randomized Controlled Trials of...
- The formation, function and regulation of amyloids...
- Autotaxin interacts with lipoprotein(a) and oxidiz...
- Haploidentical Stem Cell Transplantation in Adult ...
- IJMS, Vol. 17, Pages 838: Hereditary Predispositio...
- Icariin Inhibits Pulmonary Hypertension Induced by...
- Sensors, Vol. 16, Pages 786: Adaptive Particle Fil...
- Entropy, Vol. 18, Pages 211: A Confidence Set Anal...
- IJMS, Vol. 17, Pages 838: Hereditary Predispositio...
- Energies, Vol. 9, Pages 423: Assessing Steady-Stat...
- Materials, Vol. 9, Pages 428: Using Central Compos...
- Sustainability, Vol. 8, Pages 524: Addressing the ...
- Metals, Vol. 6, Pages 130: Vanadium Effect on a Me...
- Entropy, Vol. 18, Pages 212: Extended First Law fo...
- Molecules, Vol. 21, Pages 704: Significant Improve...
- Nutrients, Vol. 8, Pages 330: Iron, Anemia, and Ir...
- Prepulse inhibition deficits in women with PTSD
- Toxins, Vol. 8, Pages 164: Clinical Efficacy and C...
- Metals, Vol. 6, Pages 131: Melt Protection of Mg-A...
- Universe, Vol. 2, Pages 10: Reissner–Nordström Ant...
- Sports, Vol. 4, Pages 31: Heart Rate Responses dur...
- Sustainability, Vol. 8, Pages 517: Evidence of Abs...
- Materials, Vol. 9, Pages 427: Two Novel C3N4 Phase...
- Energies, Vol. 9, Pages 424: A Multi-Component Add...
- Universe, Vol. 2, Pages 9: Virial Theorem in Nonlo...
- Energies, Vol. 9, Pages 421: The Influence of Slig...
- Energies, Vol. 9, Pages 418: Three-Dimensional Fin...
- Molecules, Vol. 21, Pages 694: The Effect of New T...
- Computation, Vol. 4, Pages 21: Pore-Network Modeli...
- Molecules, Vol. 21, Pages 701: Purification, Chara...
- Polymers, Vol. 8, Pages 208: Synthesis of New Poly...
- Molecules, Vol. 21, Pages 708: Antioxidative and A...
- Polymers, Vol. 8, Pages 209: Demethylation of Whea...
- Toxins, Vol. 8, Pages 164: Clinical Efficacy and C...
- Geosciences, Vol. 6, Pages 26: Paleolimnology as a...
- JFMK, Vol. 1, Pages 240-248: Effects of Electrical...
- Computers, Vol. 5, Pages 11: Continuity-Aware Sche...
- Membranes, Vol. 6, Pages 30: Tethered and Polymer ...
- Molecules, Vol. 21, Pages 706: An Approach to Char...
- Molecules, Vol. 21, Pages 711: Molecular Genetic C...
- Minerals, Vol. 6, Pages 51: Preventive Replacement...
- Molecules, Vol. 21, Pages 683: Clematichinenoside ...
- Recycling, Vol. 1, Pages 166-177: Parameters Affec...
- Catalysts, Vol. 6, Pages 78: Solvent-Free Lipase-C...
- Sensors, Vol. 16, Pages 780: Analytical Problems i...
- Antimicrobial Susceptibility of Escherichia coli S...
- Lubricants, Vol. 4, Pages 17: Assessing Boundary F...
- Energies, Vol. 9, Pages 417: Development of a PEM ...
- Algorithms, Vol. 9, Pages 37: A New Multi-Step Ite...
- Beverages, Vol. 2, Pages 13: l-Theanine as a Funct...
-
▼
Μαΐ 30
(50)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Δευτέρα 30 Μαΐου 2016
Molecules, Vol. 21, Pages 711: Molecular Genetic Characterization of an Anthrabenzoxocinones Gene Cluster in Streptomyces Sp. FJS31-2 for the Biosynthesis of BE-24566B and Zunyimycin Ale
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.