Danning Tablets are a traditional Chinese formula showing broad clinical applications in hepatobiliary diseases and containing a diversity of bioactive chemicals. However, the chemical profiling of the formula, which serves as the material foundation of its efficacy, is really a big challenge as Danning Tablets consist of seven herbs from different origins. An ultra-performance liquid chromatography coupled to diode array detection and electrospray ionization mass spectrometry (UPLC-DAD-ESI-MS/MS) approach was developed to characterize the principal polyphenol constituents in the formula. As a result, a total of 32 constituents, including 14 anthraquinones and their glucosides, four anthrones, two naphthalene glycosides, two stilbenes and 10 flavonoids were identified based on their retention time, UV absorption and MS/MS fragmentation patterns. The sources of these compounds were also illustrated. Most of the bioactive anthraquinone derivatives were found in Rhei Radix et Rhizoma or Polygoni Cuspidati Rhizoma et Radix, which are the Emperor drugs in the formula for its clinic usage. These findings indicate the merit of using this integrated UPLC-DAD-ESI-MS/MS approach to rapidly illustrate the chemical foundation of complex formulas. The present study will facilitate the quality control of Danning Tablet formulas as well as the individual herbs.
from #Medicine via ola Kala on Inoreader http://ift.tt/27lZnnd
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Μαΐου
(630)
-
▼
Μαΐ 14
(50)
- Headspace-programmed temperature vaporization-mass...
- Ángela Molina and Joaquín GonzáIez: Pulse voltamme...
- Improved electrochemiluminescence labels for heter...
- Determination of phthalate esters at trace level f...
- Structural analysis of the activation-induced deox...
- Sensors, Vol. 16, Pages 700: Extracting Objects fo...
- Molecules, Vol. 21, Pages 647: Broadband Two-Photo...
- IJMS, Vol. 17, Pages 739: A Tumor-Specific Neo-Ant...
- IJMS, Vol. 17, Pages 735: Sirolimus and Everolimus...
- Sensors, Vol. 16, Pages 696: Stability-Aware Geogr...
- IJMS, Vol. 17, Pages 733: Pathogenetic and Therape...
- Materials, Vol. 9, Pages 375: Formation of Aluminu...
- IJMS, Vol. 17, Pages 738: Effect of AQP9 Expressio...
- IJMS, Vol. 17, Pages 733: Pathogenetic and Therape...
- IJMS, Vol. 17, Pages 739: A Tumor-Specific Neo-Ant...
- IJMS, Vol. 17, Pages 735: Sirolimus and Everolimus...
- IJMS, Vol. 17, Pages 737: Thrombin Receptor-Activa...
- IJMS, Vol. 17, Pages 738: Effect of AQP9 Expressio...
- Toxins, Vol. 8, Pages 153: The Regulatory Networks...
- Sensors, Vol. 16, Pages 701: Influences of Probe’s...
- Toxins, Vol. 8, Pages 153: The Regulatory Networks...
- Molecules, Vol. 21, Pages 636: The Suppression of ...
- Molecules, Vol. 21, Pages 633: Recent Developments...
- Molecules, Vol. 21, Pages 632: Antitumor Effect of...
- Molecules, Vol. 21, Pages 631: Characterization of...
- Molecules, Vol. 21, Pages 634: Synthesis and Biolo...
- IJMS, Vol. 17, Pages 737: Thrombin Receptor-Activa...
- Cancers, Vol. 8, Pages 49: In Hyperthermia Increas...
- Molecules, Vol. 21, Pages 617: Imidazolium Ionic L...
- IJERPH, Vol. 13, Pages 504: Epigenetic Effect of E...
- Nutrients, Vol. 8, Pages 295: Protein Intake and M...
- Electronics, Vol. 5, Pages 21: A Software Framewor...
- Tissue-specific regulation of potassium homeostasi...
- Advantages of L-3-[18F] fluoro-alpha-methyl tyrosi...
- Surgical treatment for lumbar tuberculosis by post...
- Combined active and passive heat exposure induced ...
- Skeletal muscle wasting and renewal: a pivotal rol...
- Sensors, Vol. 16, Pages 698: Erratum: Sutapun, B. ...
- Human tear proteomics and peptidomics in ophthalmo...
- Sensors, Vol. 16, Pages 697: Measurement of Moistu...
- Sustainability, Vol. 8, Pages 480: Spatial Assessm...
- The Association between Openness and Physiological...
- Increased N250 amplitudes for other-race faces ref...
- Nutrients, Vol. 8, Pages 296: Diet Quality and Ade...
- Sustainability, Vol. 8, Pages 479: Improving Freed...
- Molecules, Vol. 21, Pages 635: Mechanism of the Zn...
- IJERPH, Vol. 13, Pages 503: Physiological and Mole...
- Polymers, Vol. 8, Pages 195: Aerosol-Assisted Fast...
- Sensors, Vol. 16, Pages 693: The Real-Valued Spars...
- Laws, Vol. 5, Pages 22: A Word of Caution: Human R...
-
▼
Μαΐ 14
(50)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
https://ift.tt/2MQ8Ai8
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.