Living cell microarrays are a highly efficient cellular screening system. Due to the low number of cells required per spot, cell microarrays enable the use of primary and stem cells and provide resolution close to the single-cell level. Apart from a variety of conventional static designs, microfluidic microarray systems have also been established. An alternative format is a microarray consisting of three-dimensional cell constructs ranging from cell spheroids to cells encapsulated in hydrogel. These systems provide an in vivo-like microenvironment and are preferably used for the investigation of cellular physiology, cytotoxicity, and drug screening. Thus, many different high-tech microarray platforms are currently available. Disadvantages of many systems include their high cost, the requirement of specialized equipment for their manufacture, and the poor comparability of results between different platforms. In this article, we provide an overview of static, microfluidic, and 3D cell microarrays. In addition, we describe a simple method for the printing of living cell microarrays on modified microscope glass slides using standard DNA microarray equipment available in most laboratories. Applications in research and diagnostics are discussed, e.g., the selective and sensitive detection of biomarkers. Finally, we highlight current limitations and the future prospects of living cell microarrays.
from #Medicine via ola Kala on Inoreader http://ift.tt/1NPa637
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Μαΐου
(630)
-
▼
Μαΐ 26
(50)
- Information, Vol. 7, Pages 29: Measuring Knowledge...
- Remote Sensing, Vol. 8, Pages 449: MERIS Phytoplan...
- Energies, Vol. 9, Pages 411: Simultaneous Optimiza...
- Metals, Vol. 6, Pages 127: The Effects of Al and T...
- Microarrays, Vol. 5, Pages 11: Living Cell Microar...
- Aerospace, Vol. 3, Pages 15: Theoretical and Numer...
- Universe, Vol. 2, Pages 8: Black Holes and Exotic ...
- Atmosphere, Vol. 7, Pages 75: Stratospheric Aeroso...
- IJMS, Vol. 17, Pages 809: The miRacle in Pancreati...
- IFC(EDITORIAL BOARD)
- Potential Role of Epigenetic Mechanism in Manganes...
- Fibers, Vol. 4, Pages 18: Glass Fibre Strength—A R...
- Sustainability, Vol. 8, Pages 502: The Environment...
- Sustainability, Vol. 8, Pages 508: Impact of Inter...
- IJERPH, Vol. 13, Pages 534: Dissipation and Residu...
- Energies, Vol. 9, Pages 410: Development of a Nove...
- Sensors, Vol. 16, Pages 759: Computer-Aided Sensor...
- Applied Sciences, Vol. 6, Pages 161: Isolation, Id...
- Energies, Vol. 9, Pages 412: Analytical Model for ...
- JMSE, Vol. 4, Pages 37: Quantitative Estimates of ...
- Sustainability, Vol. 8, Pages 507: Quantitative St...
- Algorithms, Vol. 9, Pages 36: Robust Hessian Local...
- Risks, Vol. 4, Pages 16: Spouses’ Dependence acros...
- Tailored message interventions versus typical mess...
- Haemorrhoidal artery ligation versus rubber band l...
- Laparoscopic distal pancreatectomy for pancreatic ...
- Statin-induced liver Injury in an area endemic for...
- Recurrence of solid pseudopapillary neoplasms of t...
- The role of hepatitis E virus infection in Adult A...
- Postinfectious and sporadic functional gastrointes...
- Age-dependent characteristics of feedback evaluati...
- IJMS, Vol. 17, Pages 378: A Theoretical Study of t...
- Radiologic and Clinicopathologic Findings of Infla...
- Lesion Size and Iodine Quantification to Distingui...
- Low-Contrast and Low-Radiation Dose Protocol in Ca...
- Multivariate Analysis of Pleural Invasion of Perip...
- Dual-Energy CT Characteristics of Parathyroid Aden...
- Accelerated Brain Atrophy on Serial Computed Tomog...
- The Initial Exploration of Adamkiewicz Artery Comp...
- A Liver Phantom Study: CT Radiation Dose Reduction...
- Computed Tomography Perfusion of Prostate Cancer: ...
- Apparent Diffusion Coefficient and Dynamic Contras...
- Primary Extremity Liposarcoma: MRI Features, Histo...
- Beak-Like Extension of the Pancreatic Uncinate Pro...
- Retrospective Assessment of Histogram-Based Diffus...
- Evaluation of Lung Radiofrequency Ablation With Du...
- Iterative Reconstruction Results in Larger Compute...
- Symmetry, Vol. 8, Pages 39: A PT -Symmetric Dual-C...
- Microsatellite instability as a predictive factor ...
- Targeting the ecology within: The role of the gut–...
-
▼
Μαΐ 26
(50)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
https://ift.tt/2MQ8Ai8
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.