Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect

Publication date: Available online 26 March 2016
Source:Data in Brief
Author(s): Nikola Kovářová, Petr Pecina, Hana Nůsková, Marek Vrbacký, Massimo Zeviani, Tomáš Mráček, Carlo Viscomi, Josef Houštěk
This paper describes data related to a research article entitled "Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects" [1]. This paper includes data of the quantitative analysis of individual forms of respiratory chain complexes I, III and IV present in SURF1 knockout (SURF1^-/-) and control (SURF1^+/+) mouse fibroblasts and tissues and in fibroblasts of human control and patients with SURF1 gene mutation. Also it includes data demonstrating response of complex IV, cytochrome c oxidase (COX), to reversible inhibition of mitochondrial translation in SURF1^-/-mouse and SURF1 patient fibroblast cell lines.



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