Gels, Vol. 2, Pages 3: Synthesis and Characterization of New Functional Photo Cross-Linkable Smart Polymers Containing Vanillin Derivatives

The synthesis of new functional monomers based on vanillin is reported. The monomers further were used in the synthesis of different temperature-responsive photo cross-linkable polymers via free radical polymerization with N-isopropyl acrylamide and a maleimide photo cross-linker. These polymers were characterized by NMR, FTIR and UV spectroscopy, as well as gel permeation chromatography (GPC) and differential scanning calorimetry (DSC). Critical solution temperatures were determined by UV spectroscopy. Hydrogel thin films were formed by spin coating of a polymer solution over gold with adhesion promotor followed by cross-linking by UV irradiation. The swelling properties were determined by surface plasmon resonance coupled with optical waveguide spectroscopy. The swelling behavior of the hydrogel films was determined as a function of temperature. The incorporation of a dialkyl amino group compensated the hydrophobic effect of the vanillin monomer. Transition temperatures in the physiological range could be obtained.

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