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Τετάρτη 4 Νοεμβρίου 2015

OtoRhinoLaryngology New Articles,November 4th,2015

Human papillomavirus assays for FTA card-based sampling in cervical cancer screening

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
BMC Cancer - Latest Articles Feasibility and accuracy evaluation of three human papillomavirus assays for FTA card-based sampling: a pilot study in cervical cancer screening Shao-ming Wang · Wednesday, November 04, 2015, 18:04 Background: Liquid-state specimen carriers are inadequate for sample transportation in large-scale screening projects in low-resource settings, which necessitates the exploration of novel non-hazardous solid-state alternatives. Studies investigating the feasibility and accuracy of a solid-state human papillomavirus (HPV) sampling medium in combination with diffe...περισσότερα »

How Wnts Regulate Phenotype Switching in Melanoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
ScienceDirect Publication: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer The Wnts of Change: Wednesday, November 04, 2015, 18:48 Publication date: Available online 4 November 2015 *Source:*Biochimica et Biophysica Acta (BBA) - Reviews on Cancer Author(s): Marie R. Webster, Curtis Kugel, Ashani T. Weeraratna The outgrowth of metastatic and therapy-resistant subpopulations in cancer remains a critical barrier for the successful treatment of this disease. In melanoma, invasion and proliferation are uncoupled, such that highly proliferative melanoma cells are less likely to be in...περισσότερα »

In the early phase of the allergic reaction, nasal allergen challenge do not cause any significant changes in the lower airways

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Iranian Journal of Allergy, Asthma and Immunology The Safety of Nasal Allergen Challenge Test Assessed in Lower Airways Bolesław Samoliński (e.krzych@gmail.com) · Wednesday, November 04, 2015, 10:42 The aim of the study was to assess the safety of nasal allergen challenge, and the use of certain parameters applied in assessing the condition of the respiratory system. We enrolled 30 patients diagnosed with allergy to common environmental allergens and 30 healthy controls. The safety of nasal challenge tests with an allergen was assessed by measuring the concentration of exhaled nitric ... περισσότερα »

Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Clinical and Translational Allergy - Latest Articles : a multicenter, uncontrolled, observational trial Gábor Katona · Wednesday, November 04, 2015, 10:52 Background: In this observational trial, data were collected on the effectiveness and tolerability/safety of a nasal spray containing tramazoline and essential oils (trade name Rhinospray ® Plus) used for symptomatic treatment of acute rhinitis due to common cold. Methods: The trial was performed in 300 children, adolescents and adults, who were to be treated with Rhinospray ® Plus for up to 4 times per day for up to 10 days. Primar... περισσότερα »

Angiotensin Converting Enzyme Inhibitor-related Angioedema

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Iranian Journal of Allergy, Asthma and Immunology : A Case of an Unexpected Death Zehra Bahar Gey (mtamerozdemirster@gmail.com) · Wednesday, November 04, 2015, 14:42 Angioedema is an asymmetric non-pitting oedema on face, lips, tongue and mucous membranes; any delay in diagnosis and treatment can be fatal. Treatment with lisinopril as an angiotensin converting enzyme (ACE) inhibitor, can be a reason of angioedema. Here we report a case who developed oral-facial edema four years after using lisinopril/hydrochlorothiazide. Laryngeal oedema is a main cause of death in angioedema. The tre... περισσότερα »

Squamous metaplasia in Nasal Polyps

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Allergy & Rhinology Smoking is an independent association of squamous metaplasia in Chinese nasal polyps Tian Gao, Chew Lip Ng, Chunwei Li, Ying Ying Li, Chen Duan, Liang Shen, Yu Fei Jiao, Ming Liu, De Yun Wang · Wednesday, November 04, 2015, 18:40 Background Nasal polyposis demonstrates histological features of epithelial remodeling and variable inflammatory cellular infiltration. We studied a large series of Chinese nasal polyp (NP) samples to characterize these histological features and their associations with clinical characteristics. Methods A detailed histological study of nasal... περισσότερα »

Endoscopic shortening and stiffening of the vocal folds to raise the pitch

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Long-term outcome of Wednesday, November 04, 2015, 18:17 Abstract In this study, we aimed to assess the long-term effects of the mucosal layer plastic surgery of the vocal folds performed on the voices of male-to-female transgenders. This retrospective cohort study enrolled 22 patients who were operated during 2004–2010 by a combined technique of transmucosal anterior suturing and stiffening of the vocal folds through a longitudinal cordotomy incision using CO2 laser. Long-term effects were assessed based on completed ques...περισσότερα »

Hearing disorders in Turner’s syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology : a survey from Iran Wednesday, November 04, 2015, 18:17 Abstract Turner syndrome (TS) is one of the most frequently encountered sex-linked chromosomal abnormalities, occurring in one per 2,000 female births. These patients present with short stature and failure to begin puberty. In this syndrome, there are multiple organ abnormalities, including auditory disorders. TS patients were referred to the ENT clinic by a pediatric endocrinologist. A questionnaire was filled out and the patients went through a complete otologic exa... περισσότερα »

Spatial distribution of nasal polyps in the ostiomeatal complex (OMC)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Effect of distribution of nasal polyps in ostiomeatal complex on long-term outcomes after endoscopic surgery Wednesday, November 04, 2015, 18:17 Abstract The objective of the study was to elucidate the characteristics of spatial distribution of nasal polyps in the ostiomeatal complex (OMC) and the corresponding correlation with long-term quality of life in patients who underwent endoscopic sinus surgery. 107 patients with unilateral or bilateral nasal polyps who had undergone functional endoscopic sinus surgery from Septemb... περισσότερα »

Toxic inner ear lesion following otitis media with effusion

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology : a comparative CT-study regarding the morphology of the inner ear Wednesday, November 04, 2015, 18:17 Abstract Viral infections of the upper respiratory airways can lead to a delayed viral otitis media (VOM) caused by a diffusion of viruses/virus particles through the round window membrane and resulting in sensorineural hearing loss. The treatment of choice is immediate paracentesis, evacuation of all fluids from the middle ear cavity, and haemorrheological infusions. However, in some cases, persistent symptoms may be an in...περισσότερα »

Bevacizumab on vestibular schwannoma tumour size and hearing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology The effect of bevacizumab on vestibular schwannoma tumour size and hearing in patients with neurofibromatosis type 2 Wednesday, November 04, 2015, 18:17 Abstract The hallmark of neurofibromatosis type 2 (NF2) is bilateral vestibular schwannomas (VS) and severe hearing loss is common in NF2 patients. Vascular endothelial growth factor (VEGF) expression level in NF2 correlates with tumour growth rate and bevacizumab, a VEGF-binding antibody, has previously been shown to induce tumour shrinkage and improve hearing. We retrospe... περισσότερα »

“malnourished” subjects : The nutritional assessment of head and neck cancer patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology The nutritional assessment of head and neck cancer patients Wednesday, November 04, 2015, 18:17 Abstract Patients affected by head and neck cancer are particularly at risk for nutritional depletion. The aim of this study was to evaluate the nutritional status of patients affected by head and neck cancer at diagnosis. All adult patients with head and neck cancer between January 2009 and December 2013 were included. The following data were recorded: demographics, tobacco and/or alcohol consumption, weight, height, the referen... περισσότερα »

Transorbital endoscopic assisted resection of a superior orbital fissure cavernous haemangioma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology : a technical case report Wednesday, November 04, 2015, 18:17 AbstractObjectives Superior orbital fissure and orbital apex lesions are challenging to manage, regardless of the approach chosen, due to the potential morbidity. The objectives of this study are to describe an innovative, minimally invasive surgical approach addressing this critical area and to discuss its indications and outcomes. Subject A young patient presented with visual disturbances (reduction of color discrimination, central scotoma) and mild exophthalmos...περισσότερα »

Dysphagia and Eosinophilic esophagitis (EoE)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Dysphagia and health-related quality of life in patients with eosinophilic esophagitis: a long-term follow-up Wednesday, November 04, 2015, 18:17 Abstract Eosinophilic esophagitis (EoE) is a chronic immune/antigen-mediated disease, with dysphagia as the main symptom. The aim of this study was to survey symptoms and health-related quality of life in adult patients with EoE at least 1 year after diagnosis and a 2-month course of topical corticosteroids. Forty-seven consecutive patients [79 % males, mean age 49 years (range 18...περισσότερα »

Unilateral vocal cord palsy after thyroidectomy : Early voice rehabilitation with injection laryngoplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Early voice rehabilitation with injection laryngoplasty in patients with unilateral vocal cord palsy after thyroidectomy Wednesday, November 04, 2015, 18:17 Abstract Injection laryngoplasty is a safe and efficient procedure for the management of hoarseness resulting from unilateral vocal cord paralysis (VCP). However, proper timing and material of injection after the occurrence of VCP are still under discussion. This study aimed to evaluate the efficacy of early injection laryngoplasty with long-lasting soft tissue filler i... περισσότερα »

Tonsil surgery and postoperative hemorrhage

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Population-based analysis of Wednesday, November 04, 2015, 18:17 Abstract Although tonsil surgery is one of the most frequent otorhinolaryngological procedures, not many population-based regional or country-wide studies are published on the incidence of postoperative bleeding and its risk factors. 2,216 patients underwent tonsil surgery in 2012 in Thuringia, a federal state in Germany. Most frequent indications were recurrent tonsillitis (44 % of all cases), tonsillar abscess (27 %), and tonsillar hyperplasia (20 %). 29 % ... περισσότερα »

The impact of cochlear implantation on quality of life (QoL)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Quality of life and audiologic performance through the ability to phone of cochlear implant users Wednesday, November 04, 2015, 18:17 Abstract This study aimed to evaluate the impact of cochlear implantation on quality of life (QoL), using general and cochlear implant (CI) specific questionnaires and to determine the relationship of phone ability with QoL, speech recognition abilities and tinnitus. Twenty-six adult volunteers with a post-lingual profound deafness, unilaterally implanted with a CI, were included in this stud... περισσότερα »

Assessing the rhinoplasty outcome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology Assessing the rhinoplasty outcome: inter-rater variability of aesthetic perception in the light of objective facial analysis Wednesday, November 04, 2015, 18:17 Abstract The aim of this study was to assess the success of rhinoplasty by evaluating the inter-rater variability in the light of primary indication as functional or cosmetic. Subjective aesthetic perception was compared with objective facial analysis. 45 rhinoplasty patients were included in the study. 25 had cosmetic plus functional reasons with septal deviation (... περισσότερα »

Sharp neck injuries

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Latest Results for European Archives of Oto-Rhino-Laryngology in suicidal intention Wednesday, November 04, 2015, 18:17 Abstract Sharp neck injuries in suicidal intention often present as serious emergency situations with the need for an immediate diagnosis and treatment. We report our study of the clinical evolution of this emergency condition. This study investigates the cases of sharp neck injuries in suicidal intention treated at our institution between 2000 and 2010. Patient records were collected in a retrospectively reviewed and analyzed database. The current literature was co... περισσότερα »

Hypertrophic scars formation : The natural behavior of mononuclear phagocyte

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
Wound Repair and Regeneration The natural behavior of mononuclear phagocytes in HTS formation Zhensen Zhu, Jie Ding, Zengshuan Ma, Takashi Iwashina, Edward E Tredget ·Saturday, October 31, 2015, 12:00 Abstract Hypertrophic scars are caused by trauma or burn injuries to the deep dermis and are considered fibrosis in the skin. Monocytes, M1 and M2 macrophages are mononuclear phagocytes. Studies suggest that M2 macrophages are pro-fibrotic and might contribute to hypertrophic scars formation. Our lab has established a human HTS-like nude mouse model, in which the grafted human skin devel... περισσότερα »

The recognition of plastic surgery as a medical speciality

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 44 δευτερόλεπτα
Latest Results for European Journal of Plastic Surgery The recognition of plastic surgery as a medical speciality in the European economic community: a 40th anniversary Monday, November 02, 2015, 22:06 Abstract With the signing of the Treaty of Rome in 1957, the European Economic Community (EEC) was established. Its principal aim was to allow free mutual movement of goods, capital, services and persons. Medical doctors from the EEC countries were to obtain the right of establishment and practice in all six countries, as of January 1, 1968. In 1959, the national professional associatio...περισσότερα »

Freeze-dried platelet-rich plasma (FD PRP)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Latest Results for Aesthetic Plastic Surgery Growth Factor Release from Lyophilized Porcine Platelet-Rich Plasma: Quantitative Analysis and Implications for Clinical Applications Monday, November 02, 2015, 22:09 AbstractBackground Freeze-dried platelet-rich plasma (FD PRP) is of potential value for clinical applications. However, growth factors released from FD PRP have not been well studied. Our study investigates growth factor release from FD PRP preparations, compared with other PRP samples, to further facilitate such clinical use. Methods We used four experimental groups: (1) Fresh...περισσότερα »

Nasofacial Analysis Using Rhinobase ® Software

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Latest Results for Aesthetic Plastic Surgery Reliability of Wednesday, November 04, 2015, 6:28 AbstractObjective Rhinoplasty is a constant challenge for the surgeon, where the correct evaluation of facial aesthetic parameters allows harmonic changes appropriate for each patient. The aim of this study was to compare the preoperative and postoperative results of nasofacial analysis, performed by *Rhinobase* *®* software (indirect anthropometry) compared with direct anthropometry (caliper), in patients undergoing aesthetic rhinoplasty. Methods The authors assessed the reliability of usin...περισσότερα »

Patients with CRS electing ESS had worse baseline RSDI total and subdomain scores compared to those electing CMM

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Patients electing medical vs surgical treatment: emotional domain of the Rhinosinusitis Disability Index associates with treatment selection by Quinn Orb, Jess C. Mace, Adam S. DeConde, Toby O. Steele, Steve T. Cox, Timothy L. Smith, Jeremiah A. Alt via Allergy & Rhinology Background The Rhinosinusitis Disability Index (RSDI) consists of multiple subdomains shown to be useful in studying chronic rhinosinusitis (CRS). The objective of this study was to determine if RSDI subdomain scores are associated with selection of treatment modality (endoscopic sinus surgery [ESS] or continued me... περισσότερα »

Topography of Slow Sigma Power during Sleep is Associated with Processing Speed in Preschool Children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Brain Sciences, Vol. 5, Pages 494-508: by Margaret Doucette via Brain Sciences Cognitive development is influenced by maturational changes in processing speed, a construct reflecting the rapidity of executing cognitive operations. Although cognitive ability and processing speed are linked to spindles and sigma power in the sleep electroencephalogram (EEG), little is known about such associations in early childhood, a time of major neuronal refinement. We calculated EEG power for slow (10–13 Hz) and fast (13.25–17 Hz) sigma power from all-night high-density electroencephalography (EE... περισσότερα »

Continuous postoperative pain control using a multiple-hole catheter

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Continuous postoperative pain control using a multiple-hole catheter after iliac bone grafting: comparison between ropivacaine and levobupivacaine via ScienceDirect Publication: International Journal of Oral and Maxillofacial Surgery Publication date: Available online 3 November 2015 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): H. Kukidome, N. Matsuura, M. Kasahara, T. Ichinohe The aim of this study was to compare the analgesic effects of ropivacaine and levobupivacaine in continuous infiltration anaesthesia delivered via a multiple-hole catheter for the ... περισσότερα »

European Archives of Oto-Rhino-Laryngology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Erratum to: Dysphagia and health-related quality of life in patients with eosinophilic esophagitis: a long-term follow-up Sharp neck injuries in suicidal intention Abstract Sharp neck injuries in suicidal intention often present as serious emergency situations with the need for an immediate diagnosis and treatment. We report our study of the clinical evolution of this emergency condition. This study investigates the cases of sharp neck injuries in suicidal intention treated at our institution between 2000 and 2010. Patient records were collected in a retrospectively reviewed and anal... περισσότερα »

Head & Face Medicine

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Editor's note: new biomaterials for dental and craniomaxillofacial applications section Effects of a novel magnetic orthopedic appliance (MOA-III) on the dentofacial complex in mild to moderate skeletal class III children AbstractIntroduction The objective of this study was to evaluate the changes of skeletal and dental structures in mild to moderate skeletal Class III children following the use of a new magnetic orthopedic appliance (MOA-III). Methods A total of 36 patients (14 boys and 22 girls, mean age 9 years and 5 months) who presented with a mild to moderate skeletal Class III ... περισσότερα »

Journal of Voice

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Comparing Vocal Fold Contact Criteria Derived From Audio and Electroglottographic Signals Collision threshold pressure (CTP), that is, the lowest subglottal pressure facilitating vocal fold contact during phonation, is likely to reflect relevant vocal fold properties. The amplitude of an electroglottographic (EGG) signal or the amplitude of its first derivative (dEGG) has been used as criterion of such contact. Manual measurement of CTP is time consuming, making the development of a simpler, alternative method desirable. Air Pressure and Contact Quotient Measures During Different Semi... περισσότερα »

Natural Language & Linguistic Theory

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
DP-internal semantic agreement: A configurational analysis Abstract “Hybrid” nouns are known for being able to trigger either syntactic or semantic agreement, the latter typically occurring outside the noun’s projection. We document and discuss a rare example of a Hebrew noun that triggers either syntactic or semantic agreement within the DP. To explain this and other unusual patterns of nominal agreement, we propose a configurational adaptation of the concord-index distinction, originated in Wechsler and Zlatić (2003). Morphologically-rooted (=concord) features are hosted on the nou... περισσότερα »

Inferior turbinate augmentation with auricular cartilage for the treatment of empty nose syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Inferior turbinate augmentation with auricular cartilage for the treatment of empty nose syndrome Abstract Empty nose syndrome (ENS) is a potential complication of excessive resection of turbinate tissue. Patients with ENS complain of nasal obstruction despite a widely patent nasal cavity. Various implants, including autologous bone and biomaterials, have been used to reduce the width of the nasal cavity. Implantation of these grafts, however, has been limited by extrusion, infection, and resorption. We introduce a novel surgical technique that uses autologous auricular cartilage t... περισσότερα »

Langerhans cell histiocytosis involving the external auditory canal

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
: An unusual ear tumor October 30, 2015 by Kang-Wei Fan, MD; Cheng-Chien Yang, MD; Chia-I Chou, MD; Min-Tsan Shu, MD *Langerhans cell histiocytosis has an unpredictable natural history, which ranges from rapidly fatal progressive disease to spontaneous resolution.* A 10-year-old boy presented to our clinic with a 1-month history of left postauricular pain accompanied by otorrhea. On physical examination, left mastoid tenderness was noted. Otoscopic examination revealed that a soft-tissue mass with a smooth surface was occupying the entire external auditory canal, and a stalk was adhe...περισσότερα »

The need for the presurgical evaluation of nasal morphology in every individual planned for anterior maxillary segmental osteotomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Erratum to: Nasal Profile Changes Following Anterior Maxillary Segmental Osteotomy: A Lateral Cephalometric Study via Latest Results for Journal of Maxillofacial and Oral Surgery AbstractPurposeOrthognathic surgery in reference to the maxilla attempts to correct underlying skeletal deformities and improve function. Consequently, it has the potential to significantly alter the central esthetic unit of the face, the nasolabial region. In order to evaluate the nasal morphological changes which would result following anterior maxillary segmental osteotomy (superior and posterior repositi... περισσότερα »

'Vulval oedema': a conundrum!

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
Massive oedema of the vulva appears to be a sequel of an underlying systemic disease in pregnant women. Isolated vulval oedema in pregnancy is rare. Vulval oedema has been treated, depending on pathophysiology, with steroids, furosemide, albumin and continuous epidural analgaesia. We present a case of vulval oedema, where the oedema was confined to the labia minora in a healthy young pregnant woman. The patient was in pain and extreme discomfort due to the labial swelling, and caesarean section was being considered for delivery as the massive oedema would obstruct the birth canal....περισσότερα »

Journal of Oral Rehabilitation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Journal of Oral Rehabilitation Impact of shortened dental arches on oral health-related quality of life J. L. F. Antunes, H. Tan, K. G. Peres, M. A. Peres · Tuesday, October 27, 2015, 15:00 Summary This study described the prevalence of adults with shortened dental arches (SDA) in Brazil, specifically assessing the differences of oral health-related quality of life [the prevalence and severity of oral impacts on daily performance (OIDP)] by dentition status. We analysed data from the 2010 National Survey of Oral Health in Brazil, including home interviews and oral examinations. The as... περισσότερα »

Indian Journal of Oral Sciences

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Indian Journal of Oral Sciences : 2013 - 4(3) Tobacco-ending an unhealthy trend Neeta Pasricha · Sunday, November 01, 2015, 22:34 *Neeta Pasricha* Indian Journal of Oral Sciences 2015 6(2):39-40 Tags: - - - - - - Indian Journal of Oral Sciences : 2013 - 4(3) Pulp vitality tests - an overview on comparison of sensitivity and vitality A Arun · Sunday, November 01, 2015, 22:34 *A Arun, H Mythri, Dale Chachapan* Indian Journal of Oral Sciences 2015 6(2):41-46 Pulp vitality testing is only one facet of oral diagnosis, which is crucial in monitoring the health of the dental... περισσότερα »

Indian Journal of Allergy, Asthma and Immunology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Indian Journal of Allergy, Asthma and Immunology Use of beclomethasone/budesonide and formoterol adjustable dose as single maintenance and rescue therapy in the management of bronchial asthma Ketaki Satish Barve · Tuesday, October 27, 2015, 23:50 *Ketaki Satish Barve, Jyotsna Joshi, Vinaya Karkhanis* Indian Journal of Allergy, Asthma and Immunology 2014 28(1):27-34 Aims: The aim of the following study is to determine the efficacy of single maintenance and rescue therapy (SMART) with adjustable dosing in management of persistent bronchial asthma. Settings and Design: It was a follow-up, ...περισσότερα »

Hellenic Anticancer Institute C

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Hellenic Anticancer Institute Adult Pleomorphic Rhabdomyosarcoma: A Multicentre Retrospective Study Noujaim, J., Thway, K., Jones, R. L., Miah, A., Khabra, K., Langer, R., Kasper, B., Judson, I., Benson, C., Kollar, A. · Monday, October 26, 2015, 16:11 Background: Pleomorphic rhabdomyosarcoma (RMS) is a rare sub-type of RMS. Optimal treatment remains undefined. Patients and Methods: Between 1995 and 2014, 45 patients were diagnosed and treated in three tertiary sarcoma Centers (United Kingdom, Switzerland and Germany). Treatment characteristics and outcomes were analyzed. Results: The... περισσότερα »

Hellenic Anticancer Institute B

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Hellenic Anticancer Institute Investigation of Interleukin-1{beta} Polymorphisms in Prostate Cancer Yencilek, F., Yildirim, A., Yilmaz, S. G., Altinkilic, E. M., Dalan, A. B., Bastug, Y., Isbir, T. ·Monday, October 26, 2015, 16:11 Background: Cytokine-mediated immune and inflammatory responses are considered to play an important role in the pathogenesis of prostate cancer. The present study investigated certain interleukin-1β (IL1β) polymorphisms and their association with prostate cancer. Materials and Methods: Genotyping of the IL1B-31(rs 1143627 G>A) and IL1B-511(rs 16944 A<G) poly...περισσότερα »

Hellenic Anticancer Institute A

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Hellenic Anticancer Institute Intercellular HOCl-mediated Apoptosis Induction in Malignant Cells: Interplay Between NOX1-Dependent Superoxide Anion Generation and DUOX-related HOCl-generating Peroxidase Activity Pottgiesser, S. J., Heinzelmann, S., Bauer, G. · Monday, October 26, 2015, 16:11 Intercellular apoptosis-inducing HOCl signaling is discussed as a control step during oncogenesis. It is defined as a sophisticated interplay between transformed target cells and non-transformed or transformed effector cells. In this study, transformed target cells were seeded as clumps of high lo...περισσότερα »

Hellenic Anticancer Institute

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Hellenic Anticancer Institute Atypical Fibroxanthoma - Histological Diagnosis, Immunohistochemical Markers and Concepts of Therapy Koch, M., Freundl, A. J., Agaimy, A., Kiesewetter, F., Kunzel, J., Cicha, I., Alexiou, C. ·Monday, October 26, 2015, 16:11 Background: Atypical fibroxanthoma (AFX) is an uncommon, rapidly growing cutaneous neoplasm of uncertain histogenesis. Thus far, there are no guidelines for diagnosis and therapy of this tumor. Patients and Methods: We included 18 patients with 21 AFX, and 2,912 patients with a total of 2,939 AFX cited in the literature between 1962 an... περισσότερα »

Hearing

στοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Hearing The Impact of Age on Cognition Murman, Daniel L. · Sunday, November 01, 2015, 21:41 Semin Hear 2015; 36: 111-121 DOI: 10.1055/s-0035-1555115 This article reviews the cognitive changes that occur with normal aging, the structural and functional correlates of these cognitive changes, and the prevalence and cognitive effects of age-associated diseases. Understanding these age-related changes in cognition is important given our growing elderly population and the importance of cognition in maintaining functional independence and effective communication with others. The most importa...περισσότερα »

Cochlear Implants International

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Cochlear Implants International Environmental sound perception of cochlear implant users Valerie Looi, Janna Arnephy · Monday, November 02, 2015, 8:09 Abstract The purposes of this study were (1) to develop a new test of environmental sound perception, the Environmental Sounds Perception Test (EST), (2) to compare the performance of experienced cochlear implant (CI) recipients with that of age-equivalent normally hearing (NH) listeners using this new test, and (3) to pilot test its clinical use as a pre-to-post assessment tool. The closed-set EST consisted of 45 different sounds classi...περισσότερα »

Current Opinion in Allergy and Clinical Immunology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
Current Opinion in Allergy and Clinical Immunology - Current Issue Editorial introductions Friday, October 30, 2015, 23:16 [image: image]No abstract available Tags: - - - - - - Current Opinion in Allergy and Clinical Immunology - Current Issue Secondary antibody deficiencies Dhalla, Fatima; Misbah, Siraj A. · Friday, October 30, 2015, 23:16 [image: image]Purpose of review: Antibody deficiency can occur in the context of primary immune deficiency due to inherited genetic defects or secondary to a variety of causes. This review aims to summarize current data concernin... περισσότερα »

Cleft Lip Palate and Craniofacial Anomalies

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 ώρες
Cleft Lip Palate and Craniofacial Anomalies Editor's expectations from an author Karoon Agrawal · Saturday, October 24, 2015, 0:55 *Karoon Agrawal* Journal of Cleft Lip Palate and Craniofacial Anomalies 2015 2(2):87-88 Tags: - - - - - - Cleft Lip Palate and Craniofacial Anomalies Managing cleft lip and palate: The way forward Anthony F Markus · Saturday, October 24, 2015, 0:55 *Anthony F Markus* Journal of Cleft Lip Palate and Craniofacial Anomalies 2015 2(2):89-91 Tags: - - - - - - Cleft Lip Palate and Craniofacial Anomalies Primary rhinoplasty a... περισσότερα »

Bioinformatics/Medical Informatics in Traditional Medicine and Integrative Medicine

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 5 ώρες
from C via ola Kala on Inoreader http://ift.tt/1SnUpgZ via IFTTT

Ulcerative Colitis Presented as Fever and Bloody Diarrhea at Initiation of Dialysis in an Elderly Patient with End-Stage Kidney Disease

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 8 ώρες
Ulcerative colitis (UC) is a chronic inflammatory bowel disorder that mainly affects the colon and rectum. Immunological derangements are associated with the pathogenesis of UC. Many patients with UC also have chronic kidney disease, associated with immunological disorders and/or pharmacotherapy for UC. Some patients with UC may develop end-stage renal disease (ESRD) and require renal replacement therapy. However, little is known clinically about ESRD patients who develop UC or about patients with UC who develop ESRD. This report describes an elderly patient with ESRD who presente... περισσότερα »

Source Contributions of PM2.5 in the Severe Haze Episode in Hebei Cities

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 9 ώρες
Beijing-Tianjin-Hebei area is one of the most polluted areas in China. This paper used the Fifth-Generation Penn State/NCAR Mesoscale Model (MM5) and Model-3/Community Multiscale Air Quality (CMAQ) modeling system to quantify the source contribution to PM2.5 in Hebei cities in order to obtain an in-depth understanding haze process in January and February 2013, using the Multiresolution Emission Inventory for China (MEIC). The result showed that PM2.5 were mainly originated from the southern Hebei (SHB) with the fractions of 70.8% and 66.4% to Shijiazhuang, 70.6% and 63.9% to Xingta... περισσότερα »

Pre-Operative Chemoradiation for Sinonasal Undifferentiated Carcinoma of the Anterior Nasal Cavity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 ώρες
Resected Through a Lateral Nasal Flap Approach από Bhavishya Surapaneni, Sameep Kadakia, Oleh Slupchynskyj, Codrin Iacob, Roy Holliday στο American Journal of Otolaryngology AbstractIntroduction Sinonasal undifferentiated carcinoma (SNUC) is an exceedingly rare and aggressive tumor that carries a poor prognosis due to its non-specific presentation and advanced stage at time of diagnosis. Early detection and treatment are vital, with chemotherapy, radiation, and surgery all being viable options. The literature is sparse and there is no consensus for optimal treatment. In surgical cand... περισσότερα »

A far-field radio-frequency experimental exposure system

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 ώρες
with unrestrained mice από Jared Hansen στο SpringerPlus - Latest Articles Many studies have been performed on exploring the effects of radio-frequency (RF) energy on biological function in vivo. In particular, gene expression results have been inconclusive due, in part, to a lack of a standardized experimental procedure. This research describes a new far field RF exposure system for unrestrained murine models that reduces experimental error. The experimental procedure includes the materials used, the creation of a patch antenna, the uncertainty analysis of the equipment, characteri... περισσότερα »

Evaluating Latino WIC Mothers’ Perceptions of Infant’s Healthy Growth: A Formative Assessment

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 10 ώρες
Abstract *Objectives* This article reports on a formative assessment with Latino mothers in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) evaluating knowledge, attitudes and behaviors regarding healthy growth for infants and their understanding of infant growth monitoring. Further, we explored the acceptability and feasibility of mothers' monitoring their infants' growth. This assessment includes healthy growth perceptions from mothers, caregivers and from WIC staff. *Methods* Utilizing a mixed method approach, this assessment included qualitativ... περισσότερα »

Nuclear factor-{kappa}B in glioblastoma: insights into regulators and targeted therapy

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 12 ώρες
Nuclear factor-B (NF-B) is a ubiquitous transcription factor that regulates multiple aspects of cancer formation, growth, and treatment response. Glioblastoma (GBM), the most common primary malignant tumor of the central nervous system, is characterized by molecular heterogeneity, resistance to therapy, and high NF-B activity. In this review, we examine the mechanisms by which oncogenic pathways active in GBM impinge on the NF-B system, discuss the role of NF-B signaling in regulating the phenotypic properties that promote GBM and, finally, review the components of the NF-B pathway...περισσότερα »

Exercise associated hyponatraemia leading to tonic-clonic seizure

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 14 ώρες
Carl J Reynolds, Barbara J Cleaver, Sarah E Finlay<br>Aug 27, 2012; 2012:82011462-82011462<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkPb5z via IFTTT

Fatal Enterococcus durans aortic valve endocarditis: a case report and review of the literature

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 14 ώρες
Rajakrishnan Vijayakrishnan, Alwyn Rapose<br>Jun 8, 2012; 2012:22012585-22012585<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1MxCvD8 via IFTTT

Measures of Maternal Socioeconomic Status in Yemen and Association with Maternal and Child Health Outcomes

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 14 ώρες
Abstract *Background* Reliable measurement of socioeconomic status (SES) in health research requires extensive resources and can be challenging in low-income countries. We aimed to develop a set of maternal SES indices and investigate their associations with maternal and child health outcomes in rural Yemen. *Methods* We applied factor analysis based on principal component analysis extraction to construct the SES indices by capturing household attributes for 7295 women of reproductive age. Data were collected from a sub-national household survey conducted in six rural districts in... περισσότερα »

NIAC Lecture: Dr. Steve Petersen, PhD, Director, McDonnell Center for Systems Neuroscience

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 15 ώρες
[image: Steve Petersen, Ph.D., Washington University] Steve Petersen, Ph.D., Washington University Dr. Steve Petersen, PhD, Professor of Neurology, Radiology, Anatomy &amp; Neurobiology, Biomedical Engineering, Psychology and Neurological Surgery at Washington University. Dr. Petersen&#39;s lab uses behavioral and functional neuroimaging techniques (fMRI) to study neural mechanisms underlying attention, language, learning and memory as well as network properties of the brain. Their goal is to characterize the development of brain systems (e.g. the default mode network) in a way that is ... περισσότερα »

Traumatic subcutaneous haematoma causing skin necrosis

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Matthew Megson<br>Jul 21, 2011; 2011:52011427-52011427<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1MxCtev via IFTTT

Rheumatoid lung nodule

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Parikshit Sagdeo, Yathish Gattimallanahali, Girish Kakade, Balakrishnan Canchi<br>Oct 29, 2015; 2015:201521308-201521308<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP4eSN via IFTTT

Retroperitoneal panniculitis

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Norihiko Terada, Takamasa Tanaka, Takushi Fujimoto, Yasuharu Tokuda<br>Oct 21, 2015; 2015:201521267-201521267<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGWGM via IFTTT

Shark attack: the emergency presentation and management

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Conor Gouk, Daman Pasricha, Sharanya Lingathas<br>Oct 15, 2015; 2015:201521238-201521238<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP48ui via IFTTT

A case of a large, painless retroperitoneal mass causing hydronephrosis and biliary obstruction

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Joseph Attard, Christine Azzopardi, Kelvin Cortis, Jo Etienne Abela<br>Oct 15, 2015; 2015:201521242-201521242<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGTL4 via IFTTT

Fever in the returning traveller: the importance of sensitivity

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
K E J Philip, R Baddeley, M Jenkins, B Bovill<br>Oct 13, 2015; 2015:201420914-201420914<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP49hG via IFTTT

Extramedullary haematopoiesis resembling a blueberry muffin, in a neonate

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Balaganesh Karmegaraj, Sowmya Vijayakumar, Ramanathan Ramanathan, Ramesh Samikannu<br>Oct 13, 2015; 2015:201420847-201420847<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGQyI via IFTTT

Non-bacterial thrombotic endocarditis and subclinical myopericarditis in a patient with advanced rectal cancer

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Muzzammil Ali<br>Oct 12, 2015; 2015:201521282-201521282<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP465A via IFTTT

'Dilated odontoma': an incidental finding

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Ali Zakir Syed, Aravind Parachuru Venkata, Rui Amaral Mendes<br>Oct 9, 2015; 2015:201521259-201521259<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGOab via IFTTT

Interstitial ectopic pregnancy managed with local methotrexate

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Ana Macaes, Silvia Fernandes, Carla Rodrigues, Miguel Branco<br>Oct 9, 2015; 2015:201521256-201521256<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGN68 via IFTTT

A deceitful stroke, a hidden tumour

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Carlo Canepa, Aban Dasgupta<br>Oct 9, 2015; 2015:201521179-201521179<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP41ij via IFTTT

Annular alopecia areata: a morphologically rare variant

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Manish Bansal, Ajit Kumar, Alka Bansal<br>Oct 9, 2015; 2015:201521087-201521087<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP40Lm via IFTTT

A low-energy femoral shaft fracture from performing a yoga posture

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Andrew Moriarity, Prasad Ellanti, Niall Hogan<br>Oct 9, 2015; 2015:201521244-201521244<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP3ZHn via IFTTT

Correcting hypotension: be careful!

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Eilis Foran, Tarig Mohammed Abkur<br>Oct 8, 2015; 2015:201521290-201521290<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGFU5 via IFTTT

A case of digital hoarding

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Martine J van Bennekom, Rianne M Blom, Nienke Vulink, Damiaan Denys<br>Oct 8, 2015; 2015:201521081-201521081<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGEQf via IFTTT

A case of adult intussusception

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Charlotte Skinner, Clare Coyle, Gareth Parkes, William Drake<br>Oct 8, 2015; 2015:201521127-201521127<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP3Y6h via IFTTT

Another pharyngitis mimic: intraoral haematoma of the posterior wall of the pharynx in a patient on warfarin and drug-drug interaction

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Yu Watanabe, Toshikazu Abe, Yasuharu Tokuda<br>Oct 7, 2015; 2015:201520991-201520991<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGBni via IFTTT

The ulnar artery pseudoaneurysm

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Joel Woodley-Cook, Magdalena Konieczny, Martin Simons<br>Oct 6, 2015; 2015:201521279-201521279<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP3UDj via IFTTT

Acute myeloid leucaemia with trisomy 14 as a sole cytogenetic abnormality

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Jeave Reserva, Mariver Loleng, Rachel Marchalik, Basharath Khan<br>Oct 6, 2015; 2015:201521255-201521255<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1PkGzMh via IFTTT

MR features of metronidazole-induced encephalopathy

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 15 ώρες
Sonia Sandip, Ishrat Afshan, Rohit Kumar Khandelwal<br>Oct 5, 2015; 2015:201521260-201521260<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP3Tzm via IFTTT

Bowel pseudo-obstruction following an acute ST elevation myocardial infarction

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 16 ώρες
Muzzammil Ali<br>Oct 5, 2015; 2015:201521279-201521279<br>case-report from Cases via ola Kala on Inoreader http://ift.tt/1LP3QUc via IFTTT

NIAC Guest Lecture_Dr. Thomas Yeo_National University of Singapore

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 17 ώρες
[image: Dr. Thomas Yeo]Thomas Yeo is an Assistant Professor at the National University of Singapore (NUS) Department of Electrical and Computer Engineering, Clinical Imaging Research Center and Singapore Institute for Neurotechnology. He is also an affiliated faculty at Duke-NUS Graduate Medical School and Harvard Medical School. Thomas received his B.S. and M.S. from Stanford University and Ph.D. from the Massachusetts Institute of Technology. Prior to NUS, Thomas was a research fellow at Harvard University and Duke-NUS Graduate Medical School. Thomas's research involves developi...περισσότερα »

Low-intensity pulsed ultrasound treatment as an alternative to vascular bone graft surgery for a 5-year-long ulnar non-union in a patient with haemochromatosis

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
We present the case of a 75-year-old woman with haemochromatosis who developed a 5-year-long right ulnar non-union after a shortening osteotomy to correct a malunited Colles' fracture. Standard surgical treatment for ulnar non-unions was attempted on 19 March 2008 and again on 20 April 2009, but the non-union persisted on 8 May 2012, as confirmed by CT scan. Vascular bone grafting and refixation was then considered, but the patient declined this extensive operation, instead choosing to try non-invasive low-intensity pulsed ultrasound treatment with an Exogen device. Just 4 months ... περισσότερα »

Successful endovascular stroke therapy in a 103-year-old woman

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
People older than 80 years of age constitute the most rapidly growing age group in the world. Several trials confirming superior efficacy of endovascular therapy did not have an upper age limit and showed favorable treatment effects, regardless of age. Current American Heart Association/American Stroke Association guidelines do not restrict treatment based on age as long as other eligibility criteria are met. A 103-year-old woman presented 2 h after stroke onset secondary to a left internal carotid artery terminus (ICA-T) occlusion. Admission National Institutes of Health Stoke Sc... περισσότερα »

Pulmonary oedema, think beyond the heart even in the presence of severe left ventricular systolic dysfunction

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
We submit a case of a young patient with known severe left ventricular (LV) systolic impairment who presented with recurrent flash pulmonary oedema (FPO) requiring multiple high-dependency care admissions. Despite extensive optimisation of his underlying heart failure, the presentations remained frequent. Investigations for alternative diagnosis were not approached due to the presence of LV impairment and compliance being questioned. However, deteriorating renal function prompted further investigation with multiple imaging modalities, and an effective diagnosis of bilateral renal a...περισσότερα »

Successful surgical management of early esophageal cancer in a patient with cystic fibrosis post-bilateral lung transplantation

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
We present the first reported case of successful surgical management of esophageal cancer post-lung transplantation for cystic fibrosis. This case of a 42-year-old man highlights the risk factors for esophageal adenocarcinoma associated with cystic fibrosis and lung transplantation, the management options for early esophageal cancer and the surgical option chosen to minimise respiratory risks. Individualised patient care may allow for curative surgical approaches, even where complex surgery is required. from Cases via ola Kala on Inoreader http://ift.tt/1iApCQV via IFTTT

Immune recovery uveitis in a patient with previously undiagnosed cytomegalovirus retinitis

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
A 40-year-old man presented to the emergency service of the Department of Ophthalmology, Fundación Oftalmológica de Santander, Floridablanca, Colombia, with blurred vision in his right eye. Anamnesis revealed that he also had newly diagnosed stage C HIV. He had recently started highly active antiretroviral therapy (HAART). Examination disclosed intraocular inflammation, along with plain white peripheral non-exudative lesions with sparse haemorrhaging. The differential diagnosis included cytomegalovirus (CMV) retinitis and immune recovery uveitis (IRU). On follow-up, the patient's ...περισσότερα »

Neurofibromatosis 1-associated panhypopituitarism presenting as hypoglycaemic seizures and stroke-like symptoms

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
A 37-year-old man with a known history of neurofibromatosis 1 (NF1) presented within 2 days of diarrhoeal illness followed by encephalopathy, facial twitching, hypoglycaemia, hypotension, tachycardia and low-grade fever. Examination showed multiple *café-au-lait* spots and neurofibromas over the trunk, arms and legs and receptive aphasia with right homonymous hemianopia, which resolved. Workup for cardiac, inflammatory and infectious aetiologies was unrevealing. A brain MRI showed gyral swelling with increased T2 fluid-attenuated inversion recovery signal and diffusion restriction... περισσότερα »

Resolution of tachyarrhythmia-related fetal hydrops after corticosteroid administration for fetal lung maturation

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
A case of hydrops fetalis (HF) that resolved after corticosteroid therapy despite persisting fetal tachycardia of 190 bpm is reported. The fetus with confirmed normal karyotype had HF in the presence of atrial flutter and sustained ventricular rate of 200–210 bpm at gestational week (GW) 31–6/7. Aetiologies of HF other than fetal tachyarrhythmia were unlikely in this infant. The patient's family declined pharmacological treatment with maternal digoxin and desired to continue pregnancy with only intensive monitoring of fetal condition. Maternal transplacental β-methasone was given ... περισσότερα »

Buerger's disease

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
Description The angiogram and the photograph are from a 27-year-old man, a heavy smoker, who was admitted with ulcerated and necrotic lesions on the toes of both his feet, as shown in figure 1. In figure 2, the arteries are normal to the level of the mid-calf, where they abruptly occlude and are replaced by corkscrew collateral vessels, classical of thromboangiitis obliterans (Buerger's disease). This is an inflammatory disease of small-sized and medium-sized arteries and occurs almost exclusively in male heavy smokers aged 20–40 years. Treatment requires complete and immediate s...περισσότερα »

Tricuspid and mitral endocarditis due to methicillin-resistant Staphylococcus aureus exhibiting vancomycin-creep phenomenon

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
Right-sided infective endocarditis (RIE) is commonly due to *Staphylococcus aureus* and often involves the tricuspid valve (TV). A 31-year-old man with prior intravenous drug use presented with substernal pain, cough, dyspnoea and fever. Examination revealed a febrile, tachycardic male with peripheral infective endocarditis stigmata and right-heart failure. Laboratory parameters demonstrated leucocytosis, lactic acidosis and methicillin-resistant *S. aureus* (MRSA) bacteraemia. Echocardiography demonstrated multiple TV echodensities and chest imaging confirmed septic emboli. The M... περισσότερα »

Catecholamine-secreting paraganglioma: the challenges of perioperative management

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
An asymptomatic 48-year-old man presented with a right-sided neck mass. A CT scan demonstrated a lesion at the carotid bifurcation and an angiogram showed splaying of the carotid arteries. His plasma metanephrines were raised confirming a catecholamine-secreting paraganglioma. Metaiodobenzylguanidine single-photon emission CT showed focal high tracer uptake in the right of the neck. Histology revealed a tumour, arising within a nerve, composed of oval-shaped cells arranged in nested (zellballen) as well as in trabecular patterns. Immunohistochemistry was positive for neuroendocrin... περισσότερα »

A thyroid nodule mimic

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
Description A 48-year-old man, known for well-controlled hypertension over the past 8 years, was evaluated for low back pain. The clinical examination was unremarkable except for a 4 cm right-sided nodule in the region of the thyroid gland. So a clinical diagnosis of right solitary thyroid nodule was made and investigated. His biochemistry showed a high serum calcium level of 11.4 mg/dL (8.3–10.3) and phosphate of 1.4 mg/dL (2.5–5.5) with intact parathormone (PTH) of 877.8 pg/mL (8.0–74). His 24 h urine calcium level was high for his weight, with a tubular maximum excretion of ph... περισσότερα »

Dermatitis caused by metal allergy after coil embolization for unruptured cerebral aneurysm

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 23 ώρες
We report a rare case of metal-induced dermatitis after coil embolization for cerebral aneurysm. A 51-year-old woman experienced a rash around the lips and neck 3 weeks after coil embolization. Judging from the clinical course and results of several patch tests, platinum coils were considered to have induced the dermatitis. Symptoms were relieved with administration of oral steroids. This represents the first report of metal-induced dermatitis after neuroendovascular treatment. The possibility of metal allergy was difficult to suspect preoperatively. However, early evaluation and ... περισσότερα »

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