Abstract
Objectives
In Japan, an increase in the number of routine esophagogastroduodenoscopy procedures is expected because several studies have reported that endoscopy screenings have reduced gastric cancer mortality. Magnifying narrow-band imaging has been reported to be effective for accurate diagnosis of gastric abnormalities such as cancers, adenomas, and intestinal metaplasia. However, the efficacy of this method in routine esophagogastroduodenoscopy has not been clarified.
Methods
We divided 3,763 patients into two groups. The non-magnification group included 1,842 patients who underwent endoscopy screening using GIF-H260 / LUCERA-SPECTRUM between October 2014 and February 2015, while the magnification group included 1,921 patients who underwent screening using GIF-H290Z / LUCERA-ELITE between March 2015 and May 2015. In the magnification group, diagnosis of cancer was conducted using the VS classification system. We did not perform a biopsy when results were confirmed non-cancer using magnifying narrow-band imaging. If cancer was diagnosed, or when a cancer or non-cancer diagnosis was difficult, we performed a biopsy. We analyzed and compared the diagnostic performance between the two groups.
Results
The gastric biopsy rate was significantly lower in the magnification group (29%) than in the non-magnification group (41%) (p<0.001). The positive predictive value for gastric cancer was significantly higher in the magnification group (5.5%) than in the non-magnification group (2.5%) (p<0.001). Furthermore, the positive predictive value for gastric epithelial neoplasia was significantly higher the magnification group (7.9%) than the non-magnification group (3.2%) (p<0.001).
Conclusions
Magnifying narrow-band imaging improves the diagnostic performance of routine esophagogastroduodenoscopy.
This article is protected by copyright. All rights reserved.
http://ift.tt/2swlLum
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.